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- Abscisic acid bound to the Abscisic Acid Receptor (PYL2) (pdbid - 3KDI)
- Activated insulin receptor tyrosine kinase domain in complex with peptide substrate and ATP analog (1IR3)
- Active human apoptosome with procaspase-9 (5JUY)
- Active Janus Kinase (JAK) dimer complexed with cytokine receptor intracellular domain (7T6F)
- Adenylyl cyclase activator Gsalpha with GTP-gamma-S (1azt)
- AKT (Protein Kinase B) bound to a novel allosteric inhibitor is shown below (3o96)
- AKT Pleckstrin Homology (PH) domain bound to inositol (1,3,4,5)-tetrakisphosphate (1unq)
- Aligned structures of human c-Src (2SRC) and Erk2 (2Y9Q)
- Alignment of inactive AKT (3o96 with bound allosteric inhibitor) and active AKT(3cqw with bound substate)
- Alignment of MEK 1 (4U7Z) - a MAPKK - and ERK2 (5NHJ) a MAPK
- Alignment of the PKA kinase domain (1J3H A chain) and the EGFR kinase domain (2GS6)
- AlphaFold-predicted model of human Z-DNA-Binding Protein 1 (ZBP1), (Q9H171
- AlphaFold computational model of full length human PTEN (Uniprot P60484)
- AlphaFold model of monomeric human EGFR in a bilayer (P00533)
- Amphiphilic anchoring peptide AKAP-IS from AKAP binding to the docking and dimerization (D/D) domain of the RIIalpha regulatory subunit of PKA (2IZX)
- Auxin bound in the hydrophobic pocket of its receptor TIR1 ubiquitin ligase (2P1Q)
- Auxin bound to its receptor TIR1 ubiquitin ligase (2P1Q)
- Bacterial rhodopsin (1C3W)
- Bovine cyclin A (1VIN)
- Calcineurin (PP2B) complex bound to a peptide from the Na+ /H+ -exchanger 1 (6NUC)
- catalytic subunit of cAMP-dependent protein kinase complexed with MnATP and a peptide inhibitor (1ATP)
- CBD-bound full-length rat TRPV2 in nanodiscs (6U88)
- cGMP-dependent protein kinase 2 -AlphaFold Model (2Q13237)
- Class A GPCR Cannabinoid Receptor-GiComplex Structures (6KPF)
- Complex of Abscisic acid-bound PYL1 and the Protein Phosphatase 2C ABI1 (pdbid 3kdj)
- Complex of Human FasL and Its Decoy Fas Receptor DcR (4MSV)
- Cryo-EM Structure of calcium sensing receptor in complex gamma-glutamyl-valyl-glycine as a kokumi substance γ-glutamyl-valyl-glycine or γ-EVG (9J7I)
- Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA (1BF5)
- Crystal structure of the beta2 adrenergic receptor-Gs protein complex (3SN6)
- Daraxonrasib Bound 9BGC
- Diclofenac bound to the cyclooxygenase active site of COX-2 (1PXX)
- DNA binding domain of arabidopsis thaliana auxin response factor 1 (ARF1) in complex with protomor-like sequence ER7 (4LDX)
- E. Coli Transcriptional activator CadC One Component System - AlphaFold Model (P23890)
- EGFR kinase domain in complex with an ATP analog-peptide conjugate (2GS6)
- Eicosapentaenoic acid bound GPR120-Gi complex (8ID9)
- Epidermal Growth Factor Receptor - EGF Dimer (3NJP)
- Estrogen receptor DNA-binding domain bound to DNA (1HCQ)
- Fas-Tumor necrosis factor receptor superfamily member 6 AlphaFold model (P25445)
- Fragment of the nitrate/nitrite sensor histidine kinase NarQ (mutant R50K) in the symmetric holo state (IJI)
- Full human estrogen receptor computational model (P03372, AlphaFold)
- Ggust-coupled TAS2R43 with aristolochic acid I (9OXB)
- Gibberellin(GA3)-gibberellin receptor GID1L1-DELLA complex (2ZSH)
- GRB2-SH2 domain in complex with a high affinity phosphopeptide KPFpYVNVEF (1BMB)
- GRB2 N-terminal SH3 domain complexed with a ten-residue proline-rich peptide derived from SOS (1GBQ)
- G alpha (q)-phospholipase C-beta 3 structure (4GNK)
- Headpiece of integrin αIIbβ3 in the headpiece extended and open conformation (3FCU)
- Histidine kinase 4 - Cytokinin receptor 1 (CRE) from Arabidopsis thaliana (AlphaFold model) - Domain organization (Q9C5U0)
- Histidine kinase 4 - Cytokinin receptor 1 (CRE) from Arabidopsis thaliana (AlphaFold model) - PFAM Domain organization (Q9C5U0)
- Holo-calmodulin with 4 bound Ca2+ ions (1CLL)
- Human AMPK (a2b2g1) in complex with a small molecule activator SC4 (6B2E)
- Human Apaf-1 AlphaFold model (O14727)
- Human atrial natriuretic peptide receptor1 AlphaFold predicted model (P16066)
- Human Ca2+ Calmodulin- Dependent Kinase II Holoenzyme (3SOA)
- Human Cas 9 AlphaFold model (P55211)
- Human CB1 in complex with agonist AM11542 (5XRA)
- Human CDK-activating kinase (CAK) - Cyclin-dependent kinase (CDK) 7 with cyclin H and MAT1 (6xbz)
- Human cyclin-dependent kinase 2 with a bound ATP (1HCK)
- Human full-length heteromeric α1-β3-γ2L GABA(A)R in complex with diazepam (Valium) and GABA (6HUP)
- Human full-length heteromeric alpha1beta3gamma2L GABA(A)R in complex with picrotoxin and GABA (6huj)
- Human KRAS G12C covalently bound to AMG 510 (6OIM)
- Human low molecular weight protein tyrosine phosphatase bound to sulfate (1xww)
- Human mTORC1 complex (5FLC)
- Human neuronal nitric oxide synthase - Alpha Fold prediction V2
- Human neuronal nitric oxide synthase predicted by AlphaFold (P29475)
- Human prostaglandin E receptor EP3 bound to prostaglandin E2 (6AK3)
- Human Protein Phosphatase 1 Active Site Residues (4mov)
- Human Protein Tyrosine Phosphatase 1B (1-301) in complex with the inhibitor OTA (5K9W)
- Human Rack1 - a PKC Scaffolding Protein (4AOW)
- Human sodium channel 1.2-beta2-KIIIA ternary complex (6J8E)
- Human sodium channel Nav1.2-beta2-KIIIA ternary complex highlighting just the DEKA selectivity filter and the IFM and its receptor inactivation gate F1651, L1660 and N1662 (6J8E)
- Human soluble guanylate cyclase in the riociguat and NO-bound state (7D9R)
- Human synaptic alpha1beta3gamma2 GABA(A)R in complex with Ro15-4513 (7QNE)
- Human TRPV1 with capsaicin at 48 degrees Celsius in an open state (7LPE)
- Human two pore domain temperature-sensitive potassium ion channel TREK2 (K2P10.1) (4BW5)
- Human tyrosine-protein kinase C-Src in complex with AMP-PNP (2SRC)
- Inactive Serum and Glucocorticoid- Regulated Kinase 1 in Complex with AMP-PNP (2R5T)
- Inactive SGK 1 and AMP-PNP highlighting activation and catalytic features (2R5T)
- Inhibitory protein SOCS1 in complex with JAK1 kinase domain (6C7Y)
- Interactions of human wildtype KRas complex with cyclophilin and the noncovalent drug Daraxonrasib (RMC-6236) (9BG9)
- Leucine-bound Sestrin2 complex (5DJ4)
- Ligand binding domain of human estrogen receptor ERα bound to the antagonist tamoxifen (3ERT)
- Mammalian tactile channel PIEZO2 (6KG7)
- Membrane adenylyl cyclase bound to an activated stimulatory G protein 6R3Q
- Membrane domain of E. coli histidine kinase receptor KdpD (2KSF)
- Mouse mechanosensitive Piezo1 channel (5Z10)
- Mouse temperature sensitive K2P2.1 (TREK-1) potassium channels (6W84)
- mTOR - LST8 complex with bound AGS, a nonhydrolyzable ATP analog (4JSP)
- Non-receptor Protein Tyrosine Phosphatase SHP2 in Complex with Allosteric Inhibitor Pyrazolo-pyrimidinone 5 (6MDB)
- Nonpolar environment of eicosapentaenoic acid bound to GPR120 (8ID9)
- Nonpolar interactions of human wildtype KRas bound to CPA with the Daraxonrasib (9BG9)
- Odorant Binding Protein 1 from Anopheles gambiae (AgamOBP1) with DEET (N,N-Diethyl-meta-toluamide) and PEG 216 (3N7H)
- Phospho-CDK2 Cyclin A in complex with a peptide containing both the substrate and recruitment sites of CDC6(2CCI)
- Phosphorylated cyclin-dependent kinase 2 bound to cyclin A (1JST)
- Phosphotyrosine peptide bound to the SH2 domain of Fer tyrosine kinase (6KC4)
- Phytochrome (Deinococcus) Pfr form in the Photoactivated State (5C5K)
- PKC (alpha)-C2 domain complexed with Ca ions and IP3 (3GPE)
- Predicted structure of human integrin alpha-1 (AlphaFold - P56199)
- Protein Kinase C beta II (3PFQ)
- Protein phosphatase 1 (PP1) bound to the muscle glycogen-targeting subunit (Gm) and microcystin (6DNO)
- Protein phosphatase 2A core enzyme (catalytic and regulatory subunit) bound to okadaic acid
- Ras-GAP complex (1WQ1)
- Ras and SOS (a GEF) complex (1bkd)
- Second Z-DNA binding domain of human DAI (ZBP1) in complex with Z-DNA (3EYI)
- Semaglutide-bound Glucagon-Like Peptide-1 (GLP-1) Receptor in Complex with Gs protein (7KI0)
- Semaglutide in GLP-1R-bound conformation (7KI0)
- Single EGFR kinase domain showing N and C termnial lobes in complex with an ATP analog-peptide conjugate (2GS6)
- Single subunit of human Ca2+ Calmodulin- Dependent Kinase II Holoenzyme (3SOA)
- Structure of α6β1 integrin in complex with laminin-511 (7CEC)
- S aureus Universal stress protein (USP) domain of KdpD histidine kinase in complex with 2nd messenger c-di-AMP (7JI4)
- Taste receptor type 1 member 2 (TAS1R2) AlphaFold model (uniprot Q8TE23)
- Template for hovering iCn3Ds
- Ternary complex of the plant hormone abscisic acid, PYL1 (receptor) and ABI1 (phospholipase 2C) (3KDJ
- TRPM8 ion channel in complex with the menthol analog WS-12 and PI(4,5)P2 (6NR2)
- two Fas death domains bound to two FADD death domain (3EZQ)