Unit 13: Aging
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- 13.1: Aging
- This page examines aging as a decline in physiological functions, influenced by genetic and environmental factors. It discusses calorie restriction's potential benefits and its limited applicability to wild organisms. Key aging theories involve telomere shortening, DNA damage, and cellular senescence, with implications for cancer risk. Various hallmarks of aging, including mitochondrial dysfunction, genomic instability, and altered cell communication, are highlighted.
- 13.2: Telomeres
- This page discusses eukaryotic chromosomes, highlighting the role of telomeres in cellular aging and cancer proliferation, as well as potential gene therapy applications. It also covers Dolly the sheep, the first cloned mammal, whose early health issues sparked debate about the long-term effects of cloning and telomere length.