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- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/12%3A_Cancer/12.10%3A_Cancer-_The_Causes_and_Prevention_of_CancerThis page discusses how oxidative damage from metabolic by-products significantly influences aging and contributes to diseases like cancer. It highlights that antioxidants from fruits and vegetables c...This page discusses how oxidative damage from metabolic by-products significantly influences aging and contributes to diseases like cancer. It highlights that antioxidants from fruits and vegetables can help mitigate this damage, but many people don't consume enough. It also notes major cancer risk factors such as smoking and poor diet.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/Unit_IV_-_Special_Topics/29%3A_Integration_of_Mammalian_Metabolism_-_Capstone_Volume_II/29.04%3A_Skeletal_Muscle_Regulates_MetabolismSkeletal muscle plays key roles in physical movement, energy balance, and protein metabolism. It is crucial for glucose uptake and amino acid storage, influencing energy and protein metabolism across ...Skeletal muscle plays key roles in physical movement, energy balance, and protein metabolism. It is crucial for glucose uptake and amino acid storage, influencing energy and protein metabolism across the body. Conditions like sarcopenia and cachexia result from muscle loss due to aging, diseases, and metabolic shifts, leading to negative health and economic consequences.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/13%3A_AgingThis page discusses aging as a process characterized by the gradual decline in physiological functions, heightening mortality risks, especially in non-dividing cells like neurons and muscle cells. It ...This page discusses aging as a process characterized by the gradual decline in physiological functions, heightening mortality risks, especially in non-dividing cells like neurons and muscle cells. It highlights the importance of telomeres, which are protective noncoding DNA sequences at chromosome ends, in maintaining chromosome integrity and preventing fusion.
- https://bio.libretexts.org/Bookshelves/Genetics/Working_with_Molecular_Genetics_(Hardison)/Unit_II%3A_Replication_Maintenance_and_Alteration_of_the_Genetic_Material/6._DNA_replication_II%3A_Start_stop_and_control/Linear_TemplatesThe requirement of DNA polymerases to have a primer causes a problem at the ends of linear templates. The leading strand synthesis can proceed to the end of its template strand, but lagging strand syn...The requirement of DNA polymerases to have a primer causes a problem at the ends of linear templates. The leading strand synthesis can proceed to the end of its template strand, but lagging strand synthesis cannot. A 3’ overhang is left after the replication fork has finished, and part of the chromosome is not copied into new DNA. If nothing else were done, the chromosome would become progressively shorter after each round of replication.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/13%3A_Aging/13.01%3A_AgingThis page examines aging as a decline in physiological functions, influenced by genetic and environmental factors. It discusses calorie restriction's potential benefits and its limited applicability t...This page examines aging as a decline in physiological functions, influenced by genetic and environmental factors. It discusses calorie restriction's potential benefits and its limited applicability to wild organisms. Key aging theories involve telomere shortening, DNA damage, and cellular senescence, with implications for cancer risk. Various hallmarks of aging, including mitochondrial dysfunction, genomic instability, and altered cell communication, are highlighted.
