Search
- Filter Results
- Location
- Classification
- Include attachments
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/01%3A_Unit_I-_Structure_and_Catalysis/05%3A_Protein_Function/5.03%3A_B._Other_Allosteric_ProteinsThis page covers the intricacies of allosterism in biochemistry, focusing on myoglobin, hemoglobin, and various enzymes, including lactate dehydrogenase and phosphofructokinases. It discusses structur...This page covers the intricacies of allosterism in biochemistry, focusing on myoglobin, hemoglobin, and various enzymes, including lactate dehydrogenase and phosphofructokinases. It discusses structural transformations in viral enzymes and the significance of Lenacapavir as an HIV drug. The text details the kinetic behaviors of enzymes and the influence of ligand concentrations on activity.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/01%3A_Unit_I-_Structure_and_Catalysis/05%3A_Protein_Function/5.02%3A_Techniques_to_Measure_BindingIt is often essential to determine the KD for a ML complex since given that number and the concentrations of M and L in the system, we can then predict if M is bound under physiological conditions. Ag...It is often essential to determine the KD for a ML complex since given that number and the concentrations of M and L in the system, we can then predict if M is bound under physiological conditions. Again, this is important since whether M is bound or free will govern its activity. To determine KD, you need to determine ML and L at equilibrium. How can we differentiate free from bound ligand? The following techniques allow such a differentiation.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/Unit_IV_-_Special_Topics/28%3A_Biosignaling_-_Capstone_Volume_I/28.11%3A_Signaling_by_Steroid_HormonesThe page outlines learning goals for understanding steroid hormones and their action mechanisms, emphasizing their lipid-soluble nature, ability to cross cell membranes, and binding to intracellular r...The page outlines learning goals for understanding steroid hormones and their action mechanisms, emphasizing their lipid-soluble nature, ability to cross cell membranes, and binding to intracellular receptors. It describes how these complexes modulate gene transcription, implying broader physiological and pathological impacts.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/Unit_IV_-_Special_Topics/28%3A_Biosignaling_-_Capstone_Volume_I/28.02%3A_At_the_cell_membrane-_receptors_and_receptor_enzymesThe page explores detailed cell signaling processes starting at the cell membrane and moving to intracellular components like the nucleus, examining the structural features and functions of cell membr...The page explores detailed cell signaling processes starting at the cell membrane and moving to intracellular components like the nucleus, examining the structural features and functions of cell membrane receptors. It focuses on different receptor classes, including GPCRs and receptor tyrosine kinases, elaborating on their roles in signal transduction, receptor activation mechanisms, and downstream signaling pathways.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/01%3A_Unit_I-_Structure_and_Catalysis/02%3A_Water_and_its_Role_in_Life/2.05%3A_Solubility_in_an_aqueous_world_-_The_Hydrophobic_EffectThe page explores the hydrophobic effect and its significance in biochemistry. It begins with defining the hydrophobic effect, emphasizing entropy and hydrogen-bonding networks. It discusses enthalpic...The page explores the hydrophobic effect and its significance in biochemistry. It begins with defining the hydrophobic effect, emphasizing entropy and hydrogen-bonding networks. It discusses enthalpic and entropic contributions to molecular aggregation in water, highlighting ordered water structures. The page links the hydrophobic effect to protein folding, membrane formation, enzyme sites, and biomolecular organization.
