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- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/02%3A_Unit_II-_Bioenergetics_and_Metabolism/14%3A_Principles_of_Metabolic_Regulation/14.04%3A_Concentration_Control_and_Elasticity_CoefficientsThis page aims to educate biochemistry students on key aspects of metabolic control analysis by focusing on two important concepts: the concentration control coefficient and the elasticity coefficient...This page aims to educate biochemistry students on key aspects of metabolic control analysis by focusing on two important concepts: the concentration control coefficient and the elasticity coefficient. It covers the definitions and significance of these coefficients, providing insights into how enzyme activity affects metabolite concentrations and reaction rates.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/01%3A_Unit_I-_Structure_and_Catalysis/06%3A_Enzyme_Activity/6.03%3A_Kinetics_with_EnzymesThis page provides an in-depth exploration of enzyme kinetics, focusing on learning goals such as understanding kinetic principles, the Michaelis-Menten framework, and enzyme-catalyzed reactions. It c...This page provides an in-depth exploration of enzyme kinetics, focusing on learning goals such as understanding kinetic principles, the Michaelis-Menten framework, and enzyme-catalyzed reactions. It covers concepts like reaction rates, the significance of Vmax and Km, catalytic efficiency, and the use of various plots to interpret kinetic data.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/Unit_IV_-_Special_Topics/32%3A_Biochemistry_and_Climate_Change/32.11%3A__Part_3_-_A_Warmer_World%3A_Temperature_Effects_On_Chemical_ReactionsThe page explores the fundamental concepts of biochemistry related to temperature effects on biochemical processes. It outlines learning goals such as understanding the thermodynamic and kinetic basis...The page explores the fundamental concepts of biochemistry related to temperature effects on biochemical processes. It outlines learning goals such as understanding the thermodynamic and kinetic basis of temperature effects using the Arrhenius equation, examining how temperature influences enzyme activity, reaction rates, and ecological processes, and exploring biological adaptations to temperature changes.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/02%3A_Unit_II-_Bioenergetics_and_Metabolism/14%3A_Principles_of_Metabolic_Regulation/14.5%3A_Metabolism_and_Signaling%3A__The_Steady_State_Adaptation_and_HomeostasisThe page covers key biochemistry concepts, specifically focusing on enzyme kinetics, metabolic pathways, and homeostasis. It introduces hyperbolic and sigmoidal binding interactions, their implication...The page covers key biochemistry concepts, specifically focusing on enzyme kinetics, metabolic pathways, and homeostasis. It introduces hyperbolic and sigmoidal binding interactions, their implication on metabolic control, and the role of enzyme kinetics in maintaining cellular homeostasis. It also discusses adaptive motifs in metabolic regulation, including feedback systems and their contribution to metabolic stability.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/02%3A_Unit_II-_Bioenergetics_and_Metabolism/14%3A_Principles_of_Metabolic_Regulation/14.03%3A_The_Flux_Control_CoefficientThis page discusses metabolic control analysis (MCA), with a focus on the Flux Control Coefficient, used to assess enzyme contributions to metabolic flux regulation. It highlights key concepts, such a...This page discusses metabolic control analysis (MCA), with a focus on the Flux Control Coefficient, used to assess enzyme contributions to metabolic flux regulation. It highlights key concepts, such as the Summation Theorem and flux distribution across enzymes, debunking the idea of a singular "rate-limiting" enzyme.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/Unit_IV_-_Special_Topics/32%3A_Biochemistry_and_Climate_Change/32.10%3A__Part_2_-_Biohydrogen_-_HydrogenasesThis page outlines learning goals focused on hydrogenases, enzymes pivotal in biohydrogen metabolism. It emphasizes understanding hydrogenases' roles, structure-function relationships, catalytic mecha...This page outlines learning goals focused on hydrogenases, enzymes pivotal in biohydrogen metabolism. It emphasizes understanding hydrogenases' roles, structure-function relationships, catalytic mechanisms, and physiological contexts. Additionally, it explores environmental and industrial potential, factors affecting activity, and strategies for genetic and metabolic engineering to optimize hydrogenase performance.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/01%3A_Unit_I-_Structure_and_Catalysis/06%3A_Enzyme_Activity/6.06%3A_Enzyme_and_Protein_RegulationThe page outlines a comprehensive study on enzyme and protein regulation for advanced biochemistry students, focusing on various modes of regulation such as allosteric control, covalent modifications,...The page outlines a comprehensive study on enzyme and protein regulation for advanced biochemistry students, focusing on various modes of regulation such as allosteric control, covalent modifications, and proteolytic processing. It explores the physiological and pathological states linked to enzyme dysregulation and therapeutic strategies targeting these pathways.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/02%3A_Unit_II-_Bioenergetics_and_Metabolism/14%3A_Principles_of_Metabolic_Regulation/14.01%3A_Regulation_of_Metabolic_PathwaysExquisite mechanisms have evolved that control the flux of metabolites through metabolic pathways to insure that the output of the pathways meets biological demand and that energy in the form of ATP i...Exquisite mechanisms have evolved that control the flux of metabolites through metabolic pathways to insure that the output of the pathways meets biological demand and that energy in the form of ATP is not wasted by having opposing pathways run concomitantly in the same cell.
