Skip to main content
Library homepage
 

Text Color

Text Size

 

Margin Size

 

Font Type

Enable Dyslexic Font
Biology LibreTexts

Arthur Sikora Lipid rafts

( \newcommand{\kernel}{\mathrm{null}\,}\)

Exercise 1

What kinds of lipids are found in a eukaryotic cell membrane under normal conditions?

Here is a Hint if you need one

Answer

Glycerophospholipids, sphingolipids, sterols and fatty acids. 

 

Authored by Arthur Sikora.  Last update:  6/5/2023

Date of origin

Introduction

Lipid rafts are formed and dissipated over time. They are regions where specific lipids are enriched, frequently resulting in protein aggregation as well

New Heading  

[ADD TEXT]

 

 

[ADD IMAGE] (saved to your computer and uploaded with picture icon from top menu bar or drag image file to location (required from svg image)

*Use the following under your picture:

Figure x: [Add caption]

*Center Picture and Caption together using top menu bar

clipboard_ea385914366ac655f26d6cf82940d80cc.png

Lipids being removed and added to a membrane

[ADD iCn3D Model]

 

Figure x is an interactive iCn3D model of [INSERT DESCRIPTIVE TEXT - often a modified version of the title from the actual PDB page 4Q7Q

clipboard_eed6931dbe51d09a643b4e8eba78f0d84.png

NIH_NCBI_iCn3D_Banner.svgFigure 6: [INSERT THE PDB TITLE as above (INSERT PDB CODE)]. Click the image for a popup or use this external link: [https://structure.ncbi.nlm.nih.gov/i...PGDeccDmTH3Nq8].  (Copyright; author via source).  iCn3D model made by Arthur Sikora


VCellLogo.png MODEL

No inhibition (left) and Uncompetitive Inhibition (right)

NoInhi_CompInhib_MM_I_RxDiag.png

Note that the Vcell reaction diagram is the same as for competitive and uncompetive inhibition.  It doesn't explicitly show that the mixed inhibitor binds to both free and substrate-bound enzymes.  Those interactions are addressed in the mathematical equations for mixed inhibition.

Initial values No Inhibition

No_UNCOMP_inhibInitCond.png

Initial values With Uncompetitive Inhibitor

MIXED_inhibInitCond.png

I is fixed for each simulation (as it is not converted to a product) but can be changed in the simulation below.

Select Load [model name] below

 Select Start to begin the simulation.

Interactive Element

Select Plot to change Y axis min/max, then Reset and Play  |  Select Slider to change which constants are displayed |  Select About  for software information.

Move the sliders to change the constants and see changes in the displayed graph in real-time.

Time course model made using Virtual Cell (Vcell), The Center for Cell Analysis & Modeling, at UConn Health.  Funded by NIH/NIGMS (R24 GM137787); Web simulation software (miniSidewinder) from Bartholomew Jardine and Herbert M. Sauro, University of Washington.  Funded by NIH/NIGMS (RO1-GM123032-04)


 

sample modle

 

My modle 

 

 

*your text and graph

Figure x: Add caption

 

[ADD VCELL/SBML SIMULATION - REUSE]

*your text before and after insert as needed

 

New Heading

Add what you want


Arthur Sikora Lipid rafts is shared under a not declared license and was authored, remixed, and/or curated by LibreTexts.

Support Center

How can we help?