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25: RNA Metabolism

  • Page ID
    15196
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    Return to Fundamentals of Biochemistry     Search Fundamentals of Biochemistry

    • 25.1: DNA-Dependent Synthesis of RNA
      This page provides an in-depth exploration of the fundamentals of biochemistry related to RNA, focusing on transcription processes across prokaryotic and eukaryotic systems. It delves into RNA's structural similarities and differences with DNA, elaborates on the various types of RNA (mRNA, rRNA, tRNA, and ncRNAs), and describes the roles and mechanisms of transcriptional elongation and termination.
    • 25.2: RNA Processing
      The page provides a comprehensive overview of RNA processing in eukaryotic cells, highlighting essential processes such as 5??? capping, RNA splicing, and polyadenylation. It explains RNA processing's role in transforming pre-mRNA into mature mRNA, promoting mRNA stability, nuclear export, and translation initiation. RNA splicing involves removing introns and linking exons with spliceosome assistance, while polyadenylation entails adding a poly-A tail for mRNA stability.
    • 25.3: RNA-Dependent Synthesis of RNA and DNA
      The text discusses RNA-dependent polymerization, focusing on RNA-dependent RNA polymerases (RdRp) and reverse transcriptases (RNA-dependent DNA polymerases). It explores their roles in viral genome replication and retrotransposition, explaining the mechanisms of RNA synthesis by RdRp, structure and function of viral polymerases, challenges in fidelity during replication, and the evolutionary implications of error-prone replication.
    • 25.4: 26.4 References


    This page titled 25: RNA Metabolism is shared under a not declared license and was authored, remixed, and/or curated by Henry Jakubowski and Patricia Flatt.