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19.1.6: Arabidopsis Thaliana - A Model Organism

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    Arabidopsis Thaliana has become to plant biology what Drosophila melanogaster and Caenorhabditis elegans are to animal biology. Arabidopsis is an angiosperm, a dicot from the mustard family (Brassicaceae). It is popularly known as thale cress or mouse-ear cress. While it has no commercial value - in fact is considered a weed - it has proved to be an ideal organism for studying plant development.


    Fig. Arabidopsis Thaliana

    Some of its advantages as a model organism:

    • It has one of the smallest genomes in the plant kingdom: 135 x 106 base pairs of DNA distributed in 5 chromosomes (2n = 10) and almost all of which encodes its 27,407 genes.
    • Transgenic plants can be made easily using Agrobacterium tumefaciens as the vector to introduce foreign genes.
    • The plant is small - a flat rosette of leaves from which grows a flower stalk 6–12 inches high.
    • It can be easily grown in the lab in a relatively small space.
    • Development is rapid. It only takes 5– 6 weeks from seed germination to the production of a new crop of seeds.
    • It is a prolific producer of seeds (up to 10,000 per plant) making genetics studies easier.
    • Mutations can be easily generated (e.g., by irradiating the seeds or treating them with mutagenic chemicals).
    • It is normally self-pollinated so recessive mutations quickly become homozygous and thus expressed.

    Other members of its family cannot self-pollinate. They have an active system of self-incompatibility. Arabidopsis, however, has inactivating mutations in the genes — SRK and SCR - that prevent self-pollination in other members of the family.

    • However, Arabidopsis can easily be cross-pollinated to do genetic mapping and produce strains with multiple mutations.

    Many of the findings about how plants work - described throughout these pages - were learned from studies with Arabidopsis. (Photo courtesy of Nicole Hanley Markelz of the Plant Genome Research Outreach Program at Cornell University.)