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- https://bio.libretexts.org/Bookshelves/Cell_and_Molecular_Biology/Book%3A_Cells_-_Molecules_and_Mechanisms_(Wong)/14%3A_Signal_TransductionMetazoan organisms are not just conglomerations of cells that happen to stick together. The cells each have specific functions that must be coordinated with one another in order to assure the survival...Metazoan organisms are not just conglomerations of cells that happen to stick together. The cells each have specific functions that must be coordinated with one another in order to assure the survival of the organism and thus the shared survival of the component cells. If coordination is required, then a method of communication between cells is also required.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/Unit_IV_-_Special_Topics/28%3A_Biosignaling_-_Capstone_Volume_I/28.01%3A_General_Features_of_Signal_TransductionThe page provides a comprehensive overview of cell signaling tailored for biochemistry students. It delineates the process of signal transduction, emphasizing the cellular response to external signals...The page provides a comprehensive overview of cell signaling tailored for biochemistry students. It delineates the process of signal transduction, emphasizing the cellular response to external signals and the crucial roles of receptors and second messengers. It discusses the intricacies of logic gates in cellular signaling and the post-translational modifications of proteins.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/Unit_IV_-_Special_Topics/28%3A_Biosignaling_-_Capstone_Volume_I/28.16%3A_Signaling_in_PlantsThe page provides a comprehensive overview of plant signaling, focusing on key plant hormones such as auxins, cytokinins, gibberellins, abscisic acid, and ethylene. It discusses the synthesis, transpo...The page provides a comprehensive overview of plant signaling, focusing on key plant hormones such as auxins, cytokinins, gibberellins, abscisic acid, and ethylene. It discusses the synthesis, transport, perception, and signal transduction mechanisms of these hormones, highlighting their roles in coordinating plant growth, development, and stress responses.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/01%3A_Unit_I-_Structure_and_Catalysis/05%3A_Protein_Function/5.04%3A_B._The_Innate_Immune_System_PAMPs_and_DAMPs_and_InflammationThis page discusses biochemistry learning goals, focusing on protein-ligand interactions and the immune system. Topics include immune response mechanisms, the role of signaling molecules like cGAMP, a...This page discusses biochemistry learning goals, focusing on protein-ligand interactions and the immune system. Topics include immune response mechanisms, the role of signaling molecules like cGAMP, and the importance of mRNA vaccines. It explains pathogen recognition via pattern recognition receptors, inflammasome formation involving proteins like ASC, and the activation of NLRP3 by PAMPS and DAMPS.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/Unit_IV_-_Special_Topics/28%3A_Biosignaling_-_Capstone_Volume_I/28.19%3A_Signal_Transduction_-__TemperatureThis page describes the mechanisms of temperature sensing and thermoregulation in mammals, exploring the roles of different ion channels, particularly TRP and TREK channels, in detecting thermal stimu...This page describes the mechanisms of temperature sensing and thermoregulation in mammals, exploring the roles of different ion channels, particularly TRP and TREK channels, in detecting thermal stimuli. It delves into how these channels contribute to the sensation of heat, cold, and thermal pain, with TREK channels playing a key role in moderating thermoreceptor activity by hyperpolarizing cells and TRP channels depolarizing them to increase excitability.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/Unit_IV_-_Special_Topics/28%3A_Biosignaling_-_Capstone_Volume_I/28.07%3A_Calcium_SignalingThis page provides an in-depth exploration of calcium signaling in cellular processes, focusing on its role as a universal second messenger. Key areas include the regulation and dynamics of intracellu...This page provides an in-depth exploration of calcium signaling in cellular processes, focusing on its role as a universal second messenger. Key areas include the regulation and dynamics of intracellular calcium levels, the function of calcium-binding proteins like calmodulin, and the integration of calcium signaling into cellular physiology. It also discusses the pathological implications of calcium dysregulation and explores therapeutic strategies targeting the calcium signaling pathway.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/01%3A_Unit_I-_Structure_and_Catalysis/05%3A_Protein_Function/5.06%3A__Binding_-_Conformational_Selections_and_Intrinsically_Disordered_ProteinsThe page outlines learning goals related to protein-ligand interactions, focusing on induced fit and conformational selection, intrinsically disordered proteins (IDPs), and Molecular Recognition Featu...The page outlines learning goals related to protein-ligand interactions, focusing on induced fit and conformational selection, intrinsically disordered proteins (IDPs), and Molecular Recognition Features (MoRFs). It describes models of protein-ligand binding, explores mechanisms of coupling folding and binding, and discusses the role of intrinsic disorder in cellular functions.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Principles_of_Biology/01%3A_Chapter_1/07%3A_Cell_Communication/7.04%3A_Propagation_of_the_signalAfter the ligand binds to the cell-surface receptor, the activation of the receptor’s intracellular components sets off a chain of events that is called a signaling pathway or a signaling cascade. One...After the ligand binds to the cell-surface receptor, the activation of the receptor’s intracellular components sets off a chain of events that is called a signaling pathway or a signaling cascade. One of the most common chemical modifications that occurs in signaling pathways is the addition of a phosphate group (PO 4 –3 ) to a molecule such as a protein in a process called phosphorylation.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/Unit_IV_-_Special_Topics/28%3A_Biosignaling_-_Capstone_Volume_I/28.06%3A_PhosphatasesThis page discusses the fundamentals of biochemistry, specifically focusing on phosphatases and their roles in cellular signaling. Learning goals include understanding how phosphatases remove phosphat...This page discusses the fundamentals of biochemistry, specifically focusing on phosphatases and their roles in cellular signaling. Learning goals include understanding how phosphatases remove phosphate groups from proteins, classifying major phosphatase families, and examining the structural basis of phosphatase function.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/Unit_IV_-_Special_Topics/28%3A_Biosignaling_-_Capstone_Volume_I/28.04%3A__The_next_step_-_Downsteam_intracellular_signalingThis document provides a comprehensive overview of intracellular signaling, focusing on various pathways such as those mediated by PKA, PKC, AKAPs, RTKs, JAK/STAT, and Src family kinases, as well as M...This document provides a comprehensive overview of intracellular signaling, focusing on various pathways such as those mediated by PKA, PKC, AKAPs, RTKs, JAK/STAT, and Src family kinases, as well as MAPK cascades. It discusses the components involved in signal transduction, their mechanisms of activation and regulation, and the integration of different pathways to generate specific cellular responses.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/01%3A_Unit_I-_Structure_and_Catalysis/11%3A_Biological_Membranes_and_Transport/11.01%3A_Membrane_and_Membrane_ProteinsThe page outlines advanced learning goals for junior and senior biochemistry majors, focusing on membrane proteins. Key topics include classifying membrane proteins, exploring differences between tran...The page outlines advanced learning goals for junior and senior biochemistry majors, focusing on membrane proteins. Key topics include classifying membrane proteins, exploring differences between transmembrane and peripheral proteins, understanding chemical anchors like lipid modifications, studying lipid aggregates for membrane protein research, and analyzing examples of transmembrane proteins such as channels, transporters, and receptors.
