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- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/02%3A_Unit_II-_Bioenergetics_and_Metabolism/14%3A_Principles_of_Metabolic_Regulation/14.04%3A_Concentration_Control_and_Elasticity_CoefficientsThis page aims to educate biochemistry students on key aspects of metabolic control analysis by focusing on two important concepts: the concentration control coefficient and the elasticity coefficient...This page aims to educate biochemistry students on key aspects of metabolic control analysis by focusing on two important concepts: the concentration control coefficient and the elasticity coefficient. It covers the definitions and significance of these coefficients, providing insights into how enzyme activity affects metabolite concentrations and reaction rates.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/02%3A_Unit_II-_Bioenergetics_and_Metabolism/14%3A_Principles_of_Metabolic_Regulation/14.02%3A_Basic_Principles_of_Metabolic_Control_Analysis_(MCA)The page outlines learning goals and key concepts for understanding enzyme kinetics, metabolic control analysis (MCA), and steady-state dynamics in biochemical pathways. It emphasizes the importance o...The page outlines learning goals and key concepts for understanding enzyme kinetics, metabolic control analysis (MCA), and steady-state dynamics in biochemical pathways. It emphasizes the importance of studying enzymes in both isolated and integrated settings, the contrast between steady state and equilibrium, and the use of computational modeling tools like Vcell to simulate metabolic pathways.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/02%3A_Unit_II-_Bioenergetics_and_Metabolism/14%3A_Principles_of_Metabolic_Regulation/14.03%3A_The_Flux_Control_CoefficientThis page discusses metabolic control analysis (MCA), with a focus on the Flux Control Coefficient, used to assess enzyme contributions to metabolic flux regulation. It highlights key concepts, such a...This page discusses metabolic control analysis (MCA), with a focus on the Flux Control Coefficient, used to assess enzyme contributions to metabolic flux regulation. It highlights key concepts, such as the Summation Theorem and flux distribution across enzymes, debunking the idea of a singular "rate-limiting" enzyme.