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SBML_NoInhib_MixedInhibMM

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    106698
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    VCellLogo.png MODEL

    No inhibition (left) and Uncompetitive Inhibition (right)

    NoInhi_CompInhib_MM_I_RxDiag.png

    Note that the Vcell reaction diagram is the same as for competitive and uncompetive inhibition.  It doesn't explicitly show that the mixed inhibitor binds to both free and substrate-bound enzymes.  Those interactions are addressed in the mathematical equations for mixed inhibition.

    Initial values No Inhibition

    No_UNCOMP_inhibInitCond.png

    Initial values With Uncompetitive Inhibitor

    MIXED_inhibInitCond.png

    I is fixed for each simulation (as it is not converted to a product) but can be changed in the simulation below.

    Select Load [model name] below

     Select Start to begin the simulation.

    Interactive Element

    Select Plot to change Y axis min/max, then Reset and Play  |  Select Slider to change which constants are displayed |  Select About  for software information.

    Move the sliders to change the constants and see changes in the displayed graph in real-time.

    Time course model made using Virtual Cell (Vcell), The Center for Cell Analysis & Modeling, at UConn Health.  Funded by NIH/NIGMS (R24 GM137787); Web simulation software (miniSidewinder) from Bartholomew Jardine and Herbert M. Sauro, University of Washington.  Funded by NIH/NIGMS (RO1-GM123032-04)


     


    SBML_NoInhib_MixedInhibMM is shared under a not declared license and was authored, remixed, and/or curated by LibreTexts.

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