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SBML_NoINHIB_COMP_SLOW

  • Page ID
    107290
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    VCellLogo.png MODEL

    Comparison No Inhibition, Competitive Inhibition, and Slow (Competitive) Inhibition

    Vcell reaction diagram with all equations based on mass action (not Michael-Menten kinetics)

    SlowInhibition2.svg

    Concentrations

    • A, B and C (substrates), t0 = 1 uM
    • I1 and I(inhibitors) = 1 uM
    • E, E1 and E2 (enzymes) at t0 = 0.1 uM 
    • P, Q and R (products) at t0 = 0 uM

    Rate Constants

    All forward (kf) and reverse (kr) rate constants are set initially to 1 except for

    • kr2 for all reactions = 0 and kf4 = 1.

    Select Load [model name] below

     Select Start to begin the simulation.

    Interactive Element

    Only plots of P, Q and R (products) are initially shown.  Select Plot to change Y axis min/max, then Reset and Play  |  Select Slider to change which constants are displayed |  Select About  for software information.

    Move the sliders to change the constants and see changes in the displayed graph in real-time.

    Time course model made using Virtual Cell (Vcell), The Center for Cell Analysis & Modeling, at UConn Health.  Funded by NIH/NIGMS (R24 GM137787); Web simulation software (miniSidewinder) from Bartholomew Jardine and Herbert M. Sauro, University of Washington.  Funded by NIH/NIGMS (RO1-GM123032-04)


     


    SBML_NoINHIB_COMP_SLOW is shared under a not declared license and was authored, remixed, and/or curated by LibreTexts.

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