SBML_Michaelis_MentenVsSteadyState
- Page ID
- 107349
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MODEL
A comparison of the rapid equilibrium (left) and steady state (right)Michaels-Menten reaction
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| \begin{equation} v_0=\frac{k_3\left[E_O\right][S]}{K_M+S}=\frac{V_M[S]}{K_M+S} \end{equation} |
\begin{equation} v_0=\frac{k_3\left[E_O\right][S]}{\frac{k_2+k_3}{k_1}+S}=\frac{V_M[S]}{K_M+S} \end{equation} |
| Initial Condition: VM = 10 ; KM = 10; S = 50 |
Initial Conditions: k1 = 10 ; k2 = 90 ; k3 = 10 ; E0 = 1 uM; S = 50 VM = k3E0 =10; KM = (k2 + k3)/k2 = 10) |
Select Load [model name] below
Select Start to begin the simulation.
Select Plot to change Y axis min/max, then Reset and Play | Select Slider to change which constants are displayed | Select About for software information.
Move the sliders to change the constants and see changes in the displayed graph in real-time.
Time course model made using Virtual Cell (Vcell), The Center for Cell Analysis & Modeling, at UConn Health. Funded by NIH/NIGMS (R24 GM137787); Web simulation software (miniSidewinder) from Bartholomew Jardine and Herbert M. Sauro, University of Washington. Funded by NIH/NIGMS (RO1-GM123032-04)