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West Los Angeles College
Biotechnology
5: Bioinformatics- Genomics and Proteomics

5: Bioinformatics- Genomics and Proteomics

Last updated

Jul 1, 2025
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- 4.3: Applications of Recombinant DNA Technology
- 5.1: Introduction to Bioinformatics

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5.1: Introduction to Bioinformatics
Bioinformatics is a powerful interdisciplinary field of science that combines biology, computer science, mathematics, and statistics to analyze and interpret biological data. This page will introduce the areas of bioinformatics and how some of these areas are applied to fields such as medicine, drug discovery, and evolutionary biology.
5.2: Genomics
Genomics is the study of an organism’s entire genetic material. Using bioinformatics, scientists can now analyze vast amounts of genetic data, making genomics an important field. This page introduces the field of genomics and explains how one of its areas, structural genomics, is used to generate genetic and physical maps of chromosomes
5.3: Genome Sequencing
The study of genomes requires the ability to sequence DNA. This page outlines the process of Sanger sequencing and how it can be used in whole genome sequencing. This page also introduces next generation sequencing, a powerful tool that enables researchers to sequence entire genomes in a matter of hours rather than days.
5.4: Comparative Genomics
Comparative genomics is the study of the similarities and differences in the genomes of different species. By comparing genomes, scientists can draw conclusions about the genetic basis of phenotypic traits, evolutionary relationships, and biological functions. This page explains the tools and techniques used in comparing genomes, including sequence alignment algorithms like BLAST.
5.5: Functional Genomics
Functional genomics studies the functions of genes and proteins of the genome. This page outlines the tools and techniques used in functional genomics, including gene expression analysis through RNA sequencing, gene silencing using miRNA and siRNA technologies, and mutational analysis.
5.6: Proteomics
Proteomics is the large-scale study of proteins, focusing on their structure, function, interactions, and changes within biological systems. This page describes some of the techniques used in proteomics, including mass spectrometry, 2D gel electrophoresis, and chromatography.

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