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9.4: Assumptions for Computational Gene Identification

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    40969
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    The general assumptions for computational gene identification are that exons are delineated by a sequence AG at the start of the exon and a sequence of GT at the end of the exon. For protein-coding genes, the start codon (ATG) and the end codons (TAA, TGA, TAG) delineate the open reading frame. (Most of these ideas can be seen in Figure 9.3) These assumptions will be incorporated into more complex HMMs described below.

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    Figure 9.3: Delineation of Exons and Open Reading Frames


    This page titled 9.4: Assumptions for Computational Gene Identification is shared under a CC BY-NC-SA 4.0 license and was authored, remixed, and/or curated by Manolis Kellis et al. (MIT OpenCourseWare) via source content that was edited to the style and standards of the LibreTexts platform; a detailed edit history is available upon request.