Skip to main content
Biology LibreTexts

Fundamentals of Biochemistry I - Structure and Catalysis

  • Page ID
  • \( \newcommand{\vecs}[1]{\overset { \scriptstyle \rightharpoonup} {\mathbf{#1}} } \) \( \newcommand{\vecd}[1]{\overset{-\!-\!\rightharpoonup}{\vphantom{a}\smash {#1}}} \)\(\newcommand{\id}{\mathrm{id}}\) \( \newcommand{\Span}{\mathrm{span}}\) \( \newcommand{\kernel}{\mathrm{null}\,}\) \( \newcommand{\range}{\mathrm{range}\,}\) \( \newcommand{\RealPart}{\mathrm{Re}}\) \( \newcommand{\ImaginaryPart}{\mathrm{Im}}\) \( \newcommand{\Argument}{\mathrm{Arg}}\) \( \newcommand{\norm}[1]{\| #1 \|}\) \( \newcommand{\inner}[2]{\langle #1, #2 \rangle}\) \( \newcommand{\Span}{\mathrm{span}}\) \(\newcommand{\id}{\mathrm{id}}\) \( \newcommand{\Span}{\mathrm{span}}\) \( \newcommand{\kernel}{\mathrm{null}\,}\) \( \newcommand{\range}{\mathrm{range}\,}\) \( \newcommand{\RealPart}{\mathrm{Re}}\) \( \newcommand{\ImaginaryPart}{\mathrm{Im}}\) \( \newcommand{\Argument}{\mathrm{Arg}}\) \( \newcommand{\norm}[1]{\| #1 \|}\) \( \newcommand{\inner}[2]{\langle #1, #2 \rangle}\) \( \newcommand{\Span}{\mathrm{span}}\)\(\newcommand{\AA}{\unicode[.8,0]{x212B}}\)

    We explore the structure of the major classes of biomolecules, including proteins, lipids, nucleic acids, and carbohydrates. Next, we focus on their binding with other molecules, an emergent property of their structure. We then focus on additional functions of the bound complex, including diffusion and transport, catalysis and regulation. Finally, we integrate structure and function in a capstone chapter on cell signaling. We use interactive molecular models, graphs, and computational analyses to support an understanding of structure/function relationships.

    Thumbnail: Dihydrofolate reductase is inhibited by methotrexate which prevents binding of its substrate, folic acid. (CC BY 4.0 International; Thomas Shafee (modified) via Wikipedia)

    This page titled Fundamentals of Biochemistry I - Structure and Catalysis is shared under a CC BY-SA 4.0 license and was authored, remixed, and/or curated by Henry Jakubowski and Patricia Flatt.