21.6: Chapter Summary
( \newcommand{\kernel}{\mathrm{null}\,}\)
Mutations
Most mistakes in DNA replication are corrected, but if they are not, they may result in a mutation, defined as a permanent change in the DNA sequence. Mutations can be of many types, such as substitution, deletion, insertion, and trinucleotide repeat expansions. Mutations in repair genes may lead to serious consequences such as cancer. Mutations can be induced or may occur spontaneously.