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Biology LibreTexts

12.0: Overview of RNA Processing

RNA processing refers to any covalent modification to the RNA that occurs after transcription. This includes specific cleavage, addition of nucleotides, methylation or other modification of the nucleotides, and removal of introns by splicing.

RNA Precursor Modification Addition Cleavage Splicing
mRNA pre‑mRNA (hnRNA) methylation on 2'‑OH of ribose 5' cap 3' poly A cut at site for poly A; excise viral mRNA remove introns
rRNA pre‑rRNA methylation on 2'OH of ribose no excise products fr. precursor remove introns
tRNA pre‑tRNA extensive and varied CCA to 3' end yes remove introns
snRNAs ? ? 5' cap ? ?