The page on "mTOR and Nutrient Signaling" for biochemistry majors outlines learning goals to understand the role of mTOR as a regulator of cell growth and metabolism. Key areas include understanding t...The page on "mTOR and Nutrient Signaling" for biochemistry majors outlines learning goals to understand the role of mTOR as a regulator of cell growth and metabolism. Key areas include understanding the structure and function of mTOR complexes (mTORC1 and mTORC2), the upstream nutrient signals affecting mTOR activity, and the downstream cellular outcomes.
This review article discusses the role of immunometabolism, illustrating how cellular metabolism regulates immune cell function. It describes distinct metabolic signatures of immune cells and how thes...This review article discusses the role of immunometabolism, illustrating how cellular metabolism regulates immune cell function. It describes distinct metabolic signatures of immune cells and how these adapt in response to different physiological conditions such as activation and nutrient availability. Key processes like glycolysis and oxidative phosphorylation are explained as mechanisms to meet energy and biosynthesis requirements.
