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- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Map%3A_Raven_Biology_12th_Edition/16%3A_Control_of_Gene_Expression/16.03%3A_Prokaryotic_RegulationThe DNA of prokaryotes is organized into a circular chromosome supercoiled in the nucleoid region of the cell cytoplasm. Proteins that are needed for a specific function, or that are involved in the s...The DNA of prokaryotes is organized into a circular chromosome supercoiled in the nucleoid region of the cell cytoplasm. Proteins that are needed for a specific function, or that are involved in the same biochemical pathway, are encoded together in blocks called operons. For example, all of the genes needed to use lactose as an energy source are coded next to each other in the lactose (or lac) operon.
- https://bio.libretexts.org/Courses/Coastline_College/Book-_Cells_-_Molecules_and_Mechanisms_(Wong)/11%3A_Gene_Regulation/11.01%3A_Prokaryotic_Transcriptional_RegulationTo define a gene, a stretch of DNA must have a promoter, a start site, and and a stop site. In a prokaryote, these are necessary and often sufficient, but in a eukaryote, they are still necessary, but...To define a gene, a stretch of DNA must have a promoter, a start site, and and a stop site. In a prokaryote, these are necessary and often sufficient, but in a eukaryote, they are still necessary, but seldom sufficient. This chapter discusses the other elements, both positive and negative, that are used to regulate the expression (i.e. transcription) of a gene. It is primarily a story of transcription factors and the recognition elements to which they bind.
- https://bio.libretexts.org/Courses/Reedley_College/Biology_for_Science_Majors_I/15%3A_Gene_Expression/15.03%3A_Prokaryotic_Gene_RegulationThe DNA of prokaryotes is organized into a circular chromosome supercoiled in the nucleoid region of the cell cytoplasm. Proteins that are needed for a specific function, or that are involved in the s...The DNA of prokaryotes is organized into a circular chromosome supercoiled in the nucleoid region of the cell cytoplasm. Proteins that are needed for a specific function, or that are involved in the same biochemical pathway, are encoded together in blocks called operons. For example, all of the genes needed to use lactose as an energy source are coded next to each other in the lactose (or lac) operon.
- https://bio.libretexts.org/Courses/City_College_of_San_Francisco/Introduction_to_Genetics/08%3A_Genes_and_Proteins/8.07%3A_Gene_Expression/8.7.03%3A_Prokaryotic_Gene_RegulationThe DNA of prokaryotes is organized into a circular chromosome supercoiled in the nucleoid region of the cell cytoplasm. Proteins that are needed for a specific function, or that are involved in the s...The DNA of prokaryotes is organized into a circular chromosome supercoiled in the nucleoid region of the cell cytoplasm. Proteins that are needed for a specific function, or that are involved in the same biochemical pathway, are encoded together in blocks called operons. For example, all of the genes needed to use lactose as an energy source are coded next to each other in the lactose (or lac) operon.
- https://bio.libretexts.org/Workbench/Modern_Genetics/08%3A_Molecular_Genetics_II_-_Regulation_of_Gene_Expression/8.02%3A_Prokaryotic_Gene_RegulationThe DNA of prokaryotes is organized into a circular chromosome supercoiled in the nucleoid region of the cell cytoplasm. Proteins that are needed for a specific function, or that are involved in the s...The DNA of prokaryotes is organized into a circular chromosome supercoiled in the nucleoid region of the cell cytoplasm. Proteins that are needed for a specific function, or that are involved in the same biochemical pathway, are encoded together in blocks called operons. For example, all of the genes needed to use lactose as an energy source are coded next to each other in the lactose (or lac) operon.
- https://bio.libretexts.org/Bookshelves/Cell_and_Molecular_Biology/Book%3A_Cells_-_Molecules_and_Mechanisms_(Wong)/09%3A_Gene_Regulation/9.01%3A_Prokaryotic_Transcriptional_RegulationTo define a gene, a stretch of DNA must have a promoter, a start site, and and a stop site. In a prokaryote, these are necessary and often sufficient, but in a eukaryote, they are still necessary, but...To define a gene, a stretch of DNA must have a promoter, a start site, and and a stop site. In a prokaryote, these are necessary and often sufficient, but in a eukaryote, they are still necessary, but seldom sufficient. This chapter discusses the other elements, both positive and negative, that are used to regulate the expression (i.e. transcription) of a gene. It is primarily a story of transcription factors and the recognition elements to which they bind.
- https://bio.libretexts.org/Courses/Ohio_State_University/Ohio_State_University_SP22%3A_Molecular_Genetics_4606_(Chamberlin)/16%3A_Transcriptional_Regulation_(prokaryotes)/16.01%3A_The_lac_OperonEarly insights into mechanisms of transcriptional regulation came from studies of E. coli by researchers Francois Jacob & Jacques Monod. In E. coli, and many other bacteria, genes encoding several di...Early insights into mechanisms of transcriptional regulation came from studies of E. coli by researchers Francois Jacob & Jacques Monod. In E. coli, and many other bacteria, genes encoding several different proteins may be located on a single transcription unit called an operon. The genes in an operon share the same transcriptional regulation, but are translated individually. Eukaryotes generally do not group genes together as operons (exception is C. elegans and a few other species).
- https://bio.libretexts.org/Workbench/BIOL_190%3A_General_Biology_(OpenStax)/03%3A_Unit_III-_Genetics/3.06%3A_Gene_Expression/3.6.03%3A_Prokaryotic_Gene_RegulationThe DNA of prokaryotes is organized into a circular chromosome supercoiled in the nucleoid region of the cell cytoplasm. Proteins that are needed for a specific function, or that are involved in the s...The DNA of prokaryotes is organized into a circular chromosome supercoiled in the nucleoid region of the cell cytoplasm. Proteins that are needed for a specific function, or that are involved in the same biochemical pathway, are encoded together in blocks called operons. For example, all of the genes needed to use lactose as an energy source are coded next to each other in the lactose (or lac) operon.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/09%3A_Regulation_of_Gene_Expression/9.07%3A_FootprintingThis page explains the technique of footprinting, which is used to identify DNA sequences where DNA-binding proteins attach. It involves cloning the DNA with the binding site, labeling it, and digesti...This page explains the technique of footprinting, which is used to identify DNA sequences where DNA-binding proteins attach. It involves cloning the DNA with the binding site, labeling it, and digesting it with DNase I to create radioactive fragments. Protein-bound regions, such as the lac repressor, remain undigested, resulting in gaps on an autoradiogram. By comparing these gaps to a DNA sequencing ladder, the specific base sequence of the operator can be determined.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/09%3A_Regulation_of_Gene_Expression/9.01%3A_Regulation_of_Gene_Expression_in_BacteriaThis page discusses gene expression regulation in E. coli, focusing on the lac operon, which metabolizes lactose through a repressor mechanism. When lactose is present, it enables transcription by det...This page discusses gene expression regulation in E. coli, focusing on the lac operon, which metabolizes lactose through a repressor mechanism. When lactose is present, it enables transcription by detaching the repressor. The page also covers the dual control by Catabolite Activator Protein (CAP), which requires cAMP for DNA binding, allowing prioritization of glucose over lactose.
- https://bio.libretexts.org/Courses/University_of_Arkansas_Little_Rock/Genetics_BIOL3300_(Leacock)/Genetics_Textbook/06%3A_Regulation_of_Gene_Expression/6.01%3A_Prokaryotic_gene_regulationEarly insights into mechanisms of transcriptional regulation came from studies of E. coli by researchers Francois Jacob & Jacques Monod. In E. coli, and many other bacteria, genes encoding several di...Early insights into mechanisms of transcriptional regulation came from studies of E. coli by researchers Francois Jacob & Jacques Monod. In E. coli, and many other bacteria, genes encoding several different proteins may be located on a single transcription unit called an operon. The genes in an operon share the same transcriptional regulation, but are translated individually. Eukaryotes generally do not group genes together as operons (exception is C. elegans and a few other species).
