3.7.10: Review Questions
- Page ID
- 98127
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\(\newcommand{\avec}{\mathbf a}\) \(\newcommand{\bvec}{\mathbf b}\) \(\newcommand{\cvec}{\mathbf c}\) \(\newcommand{\dvec}{\mathbf d}\) \(\newcommand{\dtil}{\widetilde{\mathbf d}}\) \(\newcommand{\evec}{\mathbf e}\) \(\newcommand{\fvec}{\mathbf f}\) \(\newcommand{\nvec}{\mathbf n}\) \(\newcommand{\pvec}{\mathbf p}\) \(\newcommand{\qvec}{\mathbf q}\) \(\newcommand{\svec}{\mathbf s}\) \(\newcommand{\tvec}{\mathbf t}\) \(\newcommand{\uvec}{\mathbf u}\) \(\newcommand{\vvec}{\mathbf v}\) \(\newcommand{\wvec}{\mathbf w}\) \(\newcommand{\xvec}{\mathbf x}\) \(\newcommand{\yvec}{\mathbf y}\) \(\newcommand{\zvec}{\mathbf z}\) \(\newcommand{\rvec}{\mathbf r}\) \(\newcommand{\mvec}{\mathbf m}\) \(\newcommand{\zerovec}{\mathbf 0}\) \(\newcommand{\onevec}{\mathbf 1}\) \(\newcommand{\real}{\mathbb R}\) \(\newcommand{\twovec}[2]{\left[\begin{array}{r}#1 \\ #2 \end{array}\right]}\) \(\newcommand{\ctwovec}[2]{\left[\begin{array}{c}#1 \\ #2 \end{array}\right]}\) \(\newcommand{\threevec}[3]{\left[\begin{array}{r}#1 \\ #2 \\ #3 \end{array}\right]}\) \(\newcommand{\cthreevec}[3]{\left[\begin{array}{c}#1 \\ #2 \\ #3 \end{array}\right]}\) \(\newcommand{\fourvec}[4]{\left[\begin{array}{r}#1 \\ #2 \\ #3 \\ #4 \end{array}\right]}\) \(\newcommand{\cfourvec}[4]{\left[\begin{array}{c}#1 \\ #2 \\ #3 \\ #4 \end{array}\right]}\) \(\newcommand{\fivevec}[5]{\left[\begin{array}{r}#1 \\ #2 \\ #3 \\ #4 \\ #5 \\ \end{array}\right]}\) \(\newcommand{\cfivevec}[5]{\left[\begin{array}{c}#1 \\ #2 \\ #3 \\ #4 \\ #5 \\ \end{array}\right]}\) \(\newcommand{\mattwo}[4]{\left[\begin{array}{rr}#1 \amp #2 \\ #3 \amp #4 \\ \end{array}\right]}\) \(\newcommand{\laspan}[1]{\text{Span}\{#1\}}\) \(\newcommand{\bcal}{\cal B}\) \(\newcommand{\ccal}{\cal C}\) \(\newcommand{\scal}{\cal S}\) \(\newcommand{\wcal}{\cal W}\) \(\newcommand{\ecal}{\cal E}\) \(\newcommand{\coords}[2]{\left\{#1\right\}_{#2}}\) \(\newcommand{\gray}[1]{\color{gray}{#1}}\) \(\newcommand{\lgray}[1]{\color{lightgray}{#1}}\) \(\newcommand{\rank}{\operatorname{rank}}\) \(\newcommand{\row}{\text{Row}}\) \(\newcommand{\col}{\text{Col}}\) \(\renewcommand{\row}{\text{Row}}\) \(\newcommand{\nul}{\text{Nul}}\) \(\newcommand{\var}{\text{Var}}\) \(\newcommand{\corr}{\text{corr}}\) \(\newcommand{\len}[1]{\left|#1\right|}\) \(\newcommand{\bbar}{\overline{\bvec}}\) \(\newcommand{\bhat}{\widehat{\bvec}}\) \(\newcommand{\bperp}{\bvec^\perp}\) \(\newcommand{\xhat}{\widehat{\xvec}}\) \(\newcommand{\vhat}{\widehat{\vvec}}\) \(\newcommand{\uhat}{\widehat{\uvec}}\) \(\newcommand{\what}{\widehat{\wvec}}\) \(\newcommand{\Sighat}{\widehat{\Sigma}}\) \(\newcommand{\lt}{<}\) \(\newcommand{\gt}{>}\) \(\newcommand{\amp}{&}\) \(\definecolor{fillinmathshade}{gray}{0.9}\)GMOs are created by ________.
- generating genomic DNA fragments with restriction endonucleases
- introducing recombinant DNA into an organism by any means
- overexpressing proteins in E. coli
- all of the above
Gene therapy can be used to introduce foreign DNA into cells ________.
- for molecular cloning
- by PCR
- of tissues to cure inheritable disease
- all of the above
Insulin produced by molecular cloning:
- is of pig origin
- is a recombinant protein
- is made by the human pancreas
- is recombinant DNA
Bt toxin is considered to be ________.
- a gene for modifying insect DNA
- an organic insecticide produced by bacteria
- useful for humans to fight against insects
- a recombinant protein
The Flavr Savr Tomato:
- is a variety of vine-ripened tomato in the supermarket
- was created to have better flavor and shelf-life
- does not undergo soft rot
- all of the above
ESTs are ________.
- generated after a cDNA library is made
- unique sequences in the genome
- useful for mapping using sequence information
- all of the above
Linkage analysis ________.
- is used to create a physical map
- is based on the natural recombination process
- requires radiation hybrid mapping
- involves breaking and rejoining of DNA artificially
Genetic recombination occurs by which process?
- independent assortment
- crossing over
- chromosome segregation
- sister chromatids
Individual genetic maps in a given species are:
- genetically similar
- genetically identical
- genetically dissimilar
- not useful in species analysis
Information obtained by microscopic analysis of stained chromosomes is used in:
- radiation hybrid mapping
- sequence mapping
- RFLP mapping
- cytogenetic mapping
The chain termination method of sequencing:
- uses labeled ddNTPs
- uses only dideoxynucleotides
- uses only deoxynucleotides
- uses labeled dNTPs
Whole-genome sequencing can be used for advances in:
- the medical field
- agriculture
- biofuels
- all of the above
Sequencing an individual person’s genome
- is currently possible
- could lead to legal issues regarding discrimination and privacy
- could help make informed choices about medical treatment
- all of the above
What is the most challenging issue facing genome sequencing?
- the inability to develop fast and accurate sequencing techniques
- the ethics of using information from genomes at the individual level
- the availability and stability of DNA
- all of the above
Genomics can be used in agriculture to:
- generate new hybrid strains
- improve disease resistance
- improve yield
- all of the above
Genomics can be used on a personal level to:
- decrease transplant rejection
- predict genetic diseases that a person may have inherited
- determine the risks of genetic diseases for an individual’s children
- all of the above
What is a biomarker?
- the color coding of different genes
- a protein that is uniquely produced in a diseased state
- a molecule in the genome or proteome
- a marker that is genetically inherited
A protein signature is:
- the path followed by a protein after it is synthesized in the nucleus
- the path followed by a protein in the cytoplasm
- a protein expressed on the cell surface
- a unique set of proteins present in a diseased state