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- https://bio.libretexts.org/Courses/City_College_of_San_Francisco/Introduction_to_Genetics/07%3A_DNA_Structure_and_Function/7.05%3A_DNA_Replication_in_ProkaryotesDNA replication has been extremely well studied in prokaryotes primarily because of the small size of the genome and the mutants that are available. E. coli has 4.6 million base pairs in a single circ...DNA replication has been extremely well studied in prokaryotes primarily because of the small size of the genome and the mutants that are available. E. coli has 4.6 million base pairs in a single circular chromosome and all of it gets replicated in approximately 42 minutes, starting from a single origin of replication and proceeding around the circle in both directions. This means that approximately 1000 nucleotides are added per second. The process is rapid and occurs without many mistakes.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Map%3A_Raven_Biology_12th_Edition/14%3A_DNA-_The_Genetic_Material/14.04%3A_Prokaryotic_Replication/14.4.01%3A_DNA_Replication_in_ProkaryotesDNA replication has been extremely well studied in prokaryotes primarily because of the small size of the genome and the mutants that are available. E. coli has 4.6 million base pairs in a single circ...DNA replication has been extremely well studied in prokaryotes primarily because of the small size of the genome and the mutants that are available. E. coli has 4.6 million base pairs in a single circular chromosome and all of it gets replicated in approximately 42 minutes, starting from a single origin of replication and proceeding around the circle in both directions. This means that approximately 1000 nucleotides are added per second. The process is quite rapid and occurs without many mistake
- https://bio.libretexts.org/Courses/Universiti_Putra_Malaysia/ESC4103_-_Environmental_Microbiology_(Universiti_Putra_Malaysia)/05%3A_Microbial_Genetics/5.02%3A_Prokaryotic_Genomes/5.2B%3A_SupercoilingDNA supercoiling refers to the over- or under-winding of a DNA strand, and is an expression of the strain on that strand.
- https://bio.libretexts.org/Workbench/Bio_11A_-_Introduction_to_Biology_I/17%3A_DNA_Replication/17.03%3A_DNA_Replication_in_ProkaryotesThe nicks that remain between the newly synthesized DNA (that replaced the RNA primer) and the previously synthesized DNA are sealed by the enzyme DNA ligase, which catalyzes the formation of phosphod...The nicks that remain between the newly synthesized DNA (that replaced the RNA primer) and the previously synthesized DNA are sealed by the enzyme DNA ligase, which catalyzes the formation of phosphodiester linkages between the 3'-OH end of one nucleotide and the 5' phosphate end of the other fragment.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/General_Biology_2e_(OpenStax)/03%3A_Unit_III-_Genetics/3.04%3A_DNA_Structure_and_Function/3.4.05%3A_DNA_Replication_in_ProkaryotesDNA replication has been extremely well studied in prokaryotes primarily because of the small size of the genome and the mutants that are available. E. coli has 4.6 million base pairs in a single circ...DNA replication has been extremely well studied in prokaryotes primarily because of the small size of the genome and the mutants that are available. E. coli has 4.6 million base pairs in a single circular chromosome and all of it gets replicated in approximately 42 minutes, starting from a single origin of replication and proceeding around the circle in both directions. This means that approximately 1000 nucleotides are added per second. The process is rapid and occurs without many mistakes.
- https://bio.libretexts.org/Courses/Norco_College/OpenStax_Biology_2e_for_Norco_College/14%3A_DNA_Structure_and_Function/14.05%3A_DNA_Replication_in_ProkaryotesDNA replication has been extremely well studied in prokaryotes primarily because of the small size of the genome and the mutants that are available. E. coli has 4.6 million base pairs in a single circ...DNA replication has been extremely well studied in prokaryotes primarily because of the small size of the genome and the mutants that are available. E. coli has 4.6 million base pairs in a single circular chromosome and all of it gets replicated in approximately 42 minutes, starting from a single origin of replication and proceeding around the circle in both directions. This means that approximately 1000 nucleotides are added per second. The process is rapid and occurs without many mistakes.
- https://bio.libretexts.org/Courses/American_River_College/BIOL_400%3A_Principles_of_Biology_(Wolfe)/04%3A_Untitled_Chapter_4/15%3A_DNA_Structure_and_Function/15.04%3A_DNA_Replication_in_ProkaryotesDNA replication has been extremely well studied in prokaryotes primarily because of the small size of the genome and the mutants that are available. E. coli has 4.6 million base pairs in a single circ...DNA replication has been extremely well studied in prokaryotes primarily because of the small size of the genome and the mutants that are available. E. coli has 4.6 million base pairs in a single circular chromosome and all of it gets replicated in approximately 42 minutes, starting from a single origin of replication and proceeding around the circle in both directions. This means that approximately 1000 nucleotides are added per second. The process is rapid and occurs without many mistakes.
- https://bio.libretexts.org/Courses/Reedley_College/Biology_for_Science_Majors_I/13%3A_DNA_Structure_and_Function/13.05%3A_DNA_Replication_in_ProkaryotesDNA replication has been extremely well studied in prokaryotes primarily because of the small size of the genome and the mutants that are available. E. coli has 4.6 million base pairs in a single circ...DNA replication has been extremely well studied in prokaryotes primarily because of the small size of the genome and the mutants that are available. E. coli has 4.6 million base pairs in a single circular chromosome and all of it gets replicated in approximately 42 minutes, starting from a single origin of replication and proceeding around the circle in both directions. This means that approximately 1000 nucleotides are added per second. The process is quite rapid and occurs without many mistake
- https://bio.libretexts.org/Workbench/General_Biology_I_and_II/03%3A_Unit_III-_Genetics/3.04%3A_DNA_Structure_and_Function/3.4.05%3A_DNA_Replication_in_ProkaryotesDNA replication has been extremely well studied in prokaryotes primarily because of the small size of the genome and the mutants that are available. E. coli has 4.6 million base pairs in a single circ...DNA replication has been extremely well studied in prokaryotes primarily because of the small size of the genome and the mutants that are available. E. coli has 4.6 million base pairs in a single circular chromosome and all of it gets replicated in approximately 42 minutes, starting from a single origin of replication and proceeding around the circle in both directions. This means that approximately 1000 nucleotides are added per second. The process is rapid and occurs without many mistakes.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Principles_of_Biology/02%3A_Chapter_2/13%3A_DNA_Replication/13.01%3A_DNA_Replication_in_ProkaryotesTopoisomerase prevents the over-winding of the DNA double helix ahead of the replication fork as the DNA is opening up; it does so by causing temporary nicks in the DNA helix and then resealing it. Th...Topoisomerase prevents the over-winding of the DNA double helix ahead of the replication fork as the DNA is opening up; it does so by causing temporary nicks in the DNA helix and then resealing it. The nicks that remain between the newly synthesized DNA (that replaced the RNA primer) and the previously synthesized DNA are sealed by the enzyme DNA ligase that catalyzes the formation of phosphodiester linkage between the 3′-OH end of one nucleotide and the 5′ phosphate end of the other fragment.
- https://bio.libretexts.org/Workbench/BIOL_190%3A_General_Biology_(OpenStax)/03%3A_Unit_III-_Genetics/3.04%3A_DNA_Structure_and_Function/3.4.05%3A_DNA_Replication_in_ProkaryotesDNA replication has been extremely well studied in prokaryotes primarily because of the small size of the genome and the mutants that are available. E. coli has 4.6 million base pairs in a single circ...DNA replication has been extremely well studied in prokaryotes primarily because of the small size of the genome and the mutants that are available. E. coli has 4.6 million base pairs in a single circular chromosome and all of it gets replicated in approximately 42 minutes, starting from a single origin of replication and proceeding around the circle in both directions. This means that approximately 1000 nucleotides are added per second. The process is quite rapid and occurs without many mistake
