This page discusses metabolic control analysis (MCA), with a focus on the Flux Control Coefficient, used to assess enzyme contributions to metabolic flux regulation. It highlights key concepts, such a...This page discusses metabolic control analysis (MCA), with a focus on the Flux Control Coefficient, used to assess enzyme contributions to metabolic flux regulation. It highlights key concepts, such as the Summation Theorem and flux distribution across enzymes, debunking the idea of a singular "rate-limiting" enzyme.