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- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Map%3A_Raven_Biology_12th_Edition/19%3A_Cellular_Mechanisms_of_Development/19.03%3A_Cell_Differentiation/19.3.01%3A_Stem_CellsStem cells are cells that divide by mitosis to form either two stem cells, thus increasing the size of the stem cell "pool", or one daughter that goes on to differentiate, and one daughter that retain...Stem cells are cells that divide by mitosis to form either two stem cells, thus increasing the size of the stem cell "pool", or one daughter that goes on to differentiate, and one daughter that retains its stem-cell properties. How the choice is made is still unknown. However, several genes have been found whose activity prevents a daughter cell from differentiating.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/11%3A_Genomics/11.10%3A_Antisense_RNAThis page discusses the roles of messenger RNA (mRNA) and small RNAs in gene expression regulation and molecular biology. mRNA, often paired with antisense RNA, plays a role in genetic engineering and...This page discusses the roles of messenger RNA (mRNA) and small RNAs in gene expression regulation and molecular biology. mRNA, often paired with antisense RNA, plays a role in genetic engineering and gene expression control. RNA interference (RNAi) involves small interfering RNAs (siRNAs) and microRNAs (miRNAs) that can suppress gene expression and combat viruses.
- https://bio.libretexts.org/Courses/University_of_Arkansas_Little_Rock/BIOL3400_Developmental_Biology/02%3A_Cell_fates/2.03%3A_Stem_CellsStem cells are cells that divide by mitosis to form either two stem cells, thus increasing the size of the stem cell "pool", or one daughter that goes on to differentiate, and one daughter that retain...Stem cells are cells that divide by mitosis to form either two stem cells, thus increasing the size of the stem cell "pool", or one daughter that goes on to differentiate, and one daughter that retains its stem-cell properties. How the choice is made is still unknown. However, several genes have been found whose activity prevents a daughter cell from differentiating.
- https://bio.libretexts.org/Bookshelves/Cell_and_Molecular_Biology/Book%3A_Biofundamentals_(Klymkowsky_and_Cooper)/10%3A_Social_Systems/10.5%3A_Stem_CellsAgain, this is a stem cell-like division; the cells that remain attached to the extracellular matrix layer remain stem cell like, while those that leave the “basal cell layer” begin the process of dif...Again, this is a stem cell-like division; the cells that remain attached to the extracellular matrix layer remain stem cell like, while those that leave the “basal cell layer” begin the process of differentiation that leads, eventually, to their death (you are constantly shedding dead skin cells.) In normal skin the process of cell birth and death is balanced.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/14%3A_Embryonic_Development_and_its_Regulation/14.10%3A_RegenerationThis page discusses the regenerative abilities of flatworms and salamanders, highlighting that flatworms use pluripotent stem cells (neoblasts) and Wnt/β-catenin signaling for regeneration, while sala...This page discusses the regenerative abilities of flatworms and salamanders, highlighting that flatworms use pluripotent stem cells (neoblasts) and Wnt/β-catenin signaling for regeneration, while salamanders rely on stem cell migration and dedifferentiation. In contrast, mammals have limited regeneration, mostly in skin and liver. The research on regeneration genes, particularly Wnt, indicates possibilities for enhancing regenerative processes in other species.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/13%3A_Aging/13.02%3A_TelomeresThis page discusses eukaryotic chromosomes, highlighting the role of telomeres in cellular aging and cancer proliferation, as well as potential gene therapy applications. It also covers Dolly the shee...This page discusses eukaryotic chromosomes, highlighting the role of telomeres in cellular aging and cancer proliferation, as well as potential gene therapy applications. It also covers Dolly the sheep, the first cloned mammal, whose early health issues sparked debate about the long-term effects of cloning and telomere length.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/14%3A_Embryonic_Development_and_its_Regulation/14.08%3A_Embryonic_Stem_CellsThis page explores the properties and applications of human embryonic stem cells, including their role in cloning and regenerative medicine. It emphasizes their potential for understanding human devel...This page explores the properties and applications of human embryonic stem cells, including their role in cloning and regenerative medicine. It emphasizes their potential for understanding human development but notes ethical concerns regarding the destruction of blastocysts and challenges in ensuring compatibility for cell replacement therapies.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/General_Biology_(Boundless)/16%3A_Gene_Expression/16.12%3A_Regulating_Gene_Expression_in_Cell_Development_-_Gene_Expression_in_Stem_CellsSymmetric division maintains stem cell lines and asymmetric division yields differentiated cells.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/15%3A_The_Anatomy_and_Physiology_of_Animals/15.07%3A_Sexual_Reproduction/15.7G%3A_Human_CloningThis page discusses the successful cloning of Dolly the lamb by Dr. I. Wilmut's team in February 1997 at the Roslin Institute. The process involved fusing an adult sheep's cell nucleus with egg cells,...This page discusses the successful cloning of Dolly the lamb by Dr. I. Wilmut's team in February 1997 at the Roslin Institute. The process involved fusing an adult sheep's cell nucleus with egg cells, leading to ethical debates surrounding cloning. Dolly's lineage was verified through DNA fingerprinting, ensuring no natural mating occurred with her surrogate. The exact reasons for the cloning success are still unclear, but may relate to the properties of the cultured cells used.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/05%3A_DNA/5.14%3A_Harlequin_ChromosomesThis page discusses the behavior of chromosomes during mitosis in eukaryotes, highlighting that while most align randomly, some stem cells, particularly in skeletal muscle, may preferentially segregat...This page discusses the behavior of chromosomes during mitosis in eukaryotes, highlighting that while most align randomly, some stem cells, particularly in skeletal muscle, may preferentially segregate immortal strands to maintain original DNA and reduce mutations. It also mentions that certain chromosomes may show preferential segregation while others distribute randomly, indicating variability in this process across different cell types.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/14%3A_Embryonic_Development_and_its_RegulationThis page discusses embryogenesis, the process of embryo development from fertilization, including zygotic genome roles in tissue-specific gene expression. It highlights frog embryology from egg to ta...This page discusses embryogenesis, the process of embryo development from fertilization, including zygotic genome roles in tissue-specific gene expression. It highlights frog embryology from egg to tadpole, the cleavage process, and the importance of mRNA and protein gradients in cell differentiation. Stem cells' capabilities of replication and differentiation are noted, as well as the implications of germline mutations.
