This document provides a comprehensive overview of intracellular signaling, focusing on various pathways such as those mediated by PKA, PKC, AKAPs, RTKs, JAK/STAT, and Src family kinases, as well as M...This document provides a comprehensive overview of intracellular signaling, focusing on various pathways such as those mediated by PKA, PKC, AKAPs, RTKs, JAK/STAT, and Src family kinases, as well as MAPK cascades. It discusses the components involved in signal transduction, their mechanisms of activation and regulation, and the integration of different pathways to generate specific cellular responses.
This page explores the fundamentals of biochemistry with a focus on protein kinases, cellular signaling, and the kinome. It covers the diversity and structural features of kinases, how they are activa...This page explores the fundamentals of biochemistry with a focus on protein kinases, cellular signaling, and the kinome. It covers the diversity and structural features of kinases, how they are activated and regulated, including the detailed mechanisms of the kinome, kinases like Protein Kinase A, Protein Kinase C, and Akt, and their roles in signal transduction related to health and disease.
