This page outlines learning goals for understanding protein-ligand interactions, including binding thermodynamics, key binding constants like Kd and Ka, and the interpretation of binding curves. It co...This page outlines learning goals for understanding protein-ligand interactions, including binding thermodynamics, key binding constants like Kd and Ka, and the interpretation of binding curves. It compares one-site versus two-site binding models and explores cooperative and allosteric effects. It discusses experimental methods for measuring interactions and relates binding to protein functions in biological contexts.