The page outlines the regulation of key enzymes in the citric acid cycle and their role in cellular energy metabolism. It covers the regulation of the Pyruvate Dehydrogenase Complex, focusing on its c...The page outlines the regulation of key enzymes in the citric acid cycle and their role in cellular energy metabolism. It covers the regulation of the Pyruvate Dehydrogenase Complex, focusing on its conversion of pyruvate to acetyl-CoA and its regulation through phosphorylation and allosteric effectors. It further discusses the regulation of enzymes like citrate synthase, isocitrate dehydrogenase, and ??-ketoglutarate dehydrogenase, emphasizing feedback inhibition and substrate availability.
