This page explains how to deduce genotypes from phenotypes in a pedigree, focusing on disease inheritance. It utilizes Mendelian genetics to calculate genotype probabilities through product and sum ru...This page explains how to deduce genotypes from phenotypes in a pedigree, focusing on disease inheritance. It utilizes Mendelian genetics to calculate genotype probabilities through product and sum rules, exemplified by the likelihood of two heterozygous carriers of an autosomal recessive disease having an affected child. The text includes a pedigree illustration to estimate probabilities for individuals based on familial connections and genotypic assumptions.
