This page describes the mechanisms of temperature sensing and thermoregulation in mammals, exploring the roles of different ion channels, particularly TRP and TREK channels, in detecting thermal stimu...This page describes the mechanisms of temperature sensing and thermoregulation in mammals, exploring the roles of different ion channels, particularly TRP and TREK channels, in detecting thermal stimuli. It delves into how these channels contribute to the sensation of heat, cold, and thermal pain, with TREK channels playing a key role in moderating thermoreceptor activity by hyperpolarizing cells and TRP channels depolarizing them to increase excitability.
The page outlines learning goals for biochemistry students related to active transport mechanisms at the molecular level. It explores types of active transport, including primary and secondary; the Ma...The page outlines learning goals for biochemistry students related to active transport mechanisms at the molecular level. It explores types of active transport, including primary and secondary; the Major Facilitator Superfamily (MFS) transporters, their structure, and roles; membrane ATPases, their classes, and physiological importance; the structure and function of ABC transporters; and the nuclear pore complex's transport mechanisms.
