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- https://bio.libretexts.org/Courses/Butte_College/BC%3A_BIOL_2_-_Introduction_to_Human_Biology_(Grewal)/Text/06%3A_DNA_and_Protein_Synthesis/6.09%3A_The_Human_GenomeThe human genome refers to all the DNA of the human species. Human DNA consists of 3.3 billion base pairs and is divided into more than 20,000 genes on 23 pairs of chromosomes. The human genome also i...The human genome refers to all the DNA of the human species. Human DNA consists of 3.3 billion base pairs and is divided into more than 20,000 genes on 23 pairs of chromosomes. The human genome also includes noncoding sequences (e.g. intergenic region) of DNA.
- https://bio.libretexts.org/Courses/Minnesota_State_Community_and_Technical_College/Biology_of_Human_Concerns_(Daniels)/10%3A_DNA_and_Protein_Synthesis/10.01%3A_Case_Study-__Why_do_we_need_to_sequence_everybody's_genomePharmacogenomics is based on a special kind of genetic testing. It looks for small genetic variations that influence a person's ability to activate and deactivate drugs. Results of the tests can help ...Pharmacogenomics is based on a special kind of genetic testing. It looks for small genetic variations that influence a person's ability to activate and deactivate drugs. Results of the tests can help doctors choose the best drug and most effective dose for a given patient. Many drugs need to be activated by the patient's own enzymes, and inherited variations in enzymes may affect how quickly or efficiently this happens.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/General_Biology_2e_(OpenStax)/03%3A_Unit_III-_Genetics/3.07%3A_Biotechnology_and_Genomics/3.7.05%3A_Applying_GenomicsThe introduction of DNA sequencing and whole genome sequencing projects, particularly the Human Genome project, has expanded the applicability of DNA sequence information. Genomics is now being used i...The introduction of DNA sequencing and whole genome sequencing projects, particularly the Human Genome project, has expanded the applicability of DNA sequence information. Genomics is now being used in a wide variety of fields, such as metagenomics, pharmacogenomics, and mitochondrial genomics. The most commonly known application of genomics is to understand and find cures for diseases.
- https://bio.libretexts.org/Courses/Manchester_Community_College_(MCC)/BIOL_106%3A_Essentials_of_Anatomy_and_Physiology_(Anzalone)/03%3A_Cell_Structure_and_Function/3.18%3A_The_Human_GenomeThe human genome refers to all the DNA of the human species. Human DNA consists of 3.3 billion base pairs and is divided into more than 20,000 genes on 23 pairs of chromosomes. The human genome also i...The human genome refers to all the DNA of the human species. Human DNA consists of 3.3 billion base pairs and is divided into more than 20,000 genes on 23 pairs of chromosomes. The human genome also includes noncoding sequences (e.g. intergenic region) of DNA.
- https://bio.libretexts.org/Courses/Butte_College/BC%3A_BIOL_2_-_Introduction_to_Human_Biology_(Grewal)/Text/07%3A_Cell_Reproduction/7.1%3A_Case_Study%3A_Genetic_Similarities_and_DifferencesSteve asked his doctor about Pharmocogenomics. The doctor explains to Steve that Pharmacogenomics is the tailoring of drug treatments to people’s genetic makeup, a form of ‘personalized medicine’.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/01%3A_Unit_I-_Structure_and_Catalysis/09%3A_Investigating_DNA/9.02%3A_BioinformaticsThe introduction discusses the significant impact of technological advances on science, particularly in generating and managing "omic" data. The complexities in understanding this data in biology and ...The introduction discusses the significant impact of technological advances on science, particularly in generating and managing "omic" data. The complexities in understanding this data in biology and bioinformatics present challenges that are addressed through new computational tools and interdisciplinary approaches.
- https://bio.libretexts.org/Bookshelves/Human_Biology/Human_Biology_(Wakim_and_Grewal)/06%3A_DNA_and_Protein_Synthesis/6.01%3A_Case_Study%3A_Why_do_we_need_to_sequence_everybody's_genomePharmacogenomics is based on a special kind of genetic testing. It looks for small genetic variations that influence a person's ability to activate and deactivate drugs. Results of the tests can help ...Pharmacogenomics is based on a special kind of genetic testing. It looks for small genetic variations that influence a person's ability to activate and deactivate drugs. Results of the tests can help doctors choose the best drug and most effective dose for a given patient. Many drugs need to be activated by the patient's own enzymes, and inherited variations in enzymes may affect how quickly or efficiently this happens.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Principles_of_Biology/02%3A_Chapter_2/20%3A_Biotechnology/20.05%3A_Applying_GenomicsThe results of GWAS can be used in two ways: the genetic differences may be used as markers for susceptibility to the disease in undiagnosed individuals, and the particular genes identified can be tar...The results of GWAS can be used in two ways: the genetic differences may be used as markers for susceptibility to the disease in undiagnosed individuals, and the particular genes identified can be targets for research into the molecular pathway of the disease and potential therapies. Studying changes in gene expression could provide information about the gene transcription profile in the presence of the drug, which can be used as an early indicator of the potential for toxic effects.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/General_Biology_(Boundless)/17%3A_Biotechnology_and_Genomics/17.04%3A_Applying_Genomics/17.4B%3A_Pharmacogenomics_Toxicogenomics_and_MetagenomicsThe effectiveness and safety of drugs can be determined through pharmacogenomics.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Concepts_in_Biology_(OpenStax)/10%3A_Biotechnology/10.03%3A_Genomics_and_ProteomicsGenome mapping is similar to solving a big, complicated puzzle with pieces of information coming from laboratories all over the world. Genetic maps provide an outline for the location of genes within ...Genome mapping is similar to solving a big, complicated puzzle with pieces of information coming from laboratories all over the world. Genetic maps provide an outline for the location of genes within a genome, and they estimate the distance between genes and genetic markers on the basis of the recombination frequency during meiosis. Physical maps provide detailed information about the physical distance between the genes. The most detailed information is available through sequence mapping.
- https://bio.libretexts.org/Courses/Minnesota_State_Community_and_Technical_College/Biology_of_Human_Concerns_(Daniels)/10%3A_DNA_and_Protein_Synthesis/10.09%3A_The_Human_GenomeThe human genome refers to all the DNA of the human species. Human DNA consists of 3.3 billion base pairs and is divided into more than 20,000 genes on 23 pairs of chromosomes. The human genome also i...The human genome refers to all the DNA of the human species. Human DNA consists of 3.3 billion base pairs and is divided into more than 20,000 genes on 23 pairs of chromosomes. The human genome also includes noncoding sequences (e.g. intergenic region) of DNA.
