The page on "mTOR and Nutrient Signaling" for biochemistry majors outlines learning goals to understand the role of mTOR as a regulator of cell growth and metabolism. Key areas include understanding t...The page on "mTOR and Nutrient Signaling" for biochemistry majors outlines learning goals to understand the role of mTOR as a regulator of cell growth and metabolism. Key areas include understanding the structure and function of mTOR complexes (mTORC1 and mTORC2), the upstream nutrient signals affecting mTOR activity, and the downstream cellular outcomes.
This page explores the fundamentals of biochemistry with a focus on protein kinases, cellular signaling, and the kinome. It covers the diversity and structural features of kinases, how they are activa...This page explores the fundamentals of biochemistry with a focus on protein kinases, cellular signaling, and the kinome. It covers the diversity and structural features of kinases, how they are activated and regulated, including the detailed mechanisms of the kinome, kinases like Protein Kinase A, Protein Kinase C, and Akt, and their roles in signal transduction related to health and disease.