This page outlines six hallmarks of cancer: growth signal autonomy, insensitivity to growth inhibitory signals, evasion of apoptosis, unlimited reproductive potential, sustained angiogenesis, invasion...This page outlines six hallmarks of cancer: growth signal autonomy, insensitivity to growth inhibitory signals, evasion of apoptosis, unlimited reproductive potential, sustained angiogenesis, invasion and metastasis, deregulated metabolism, immune evasion, chromosomal instability, and inflammation. These traits explain how cancer cells proliferate uncontrollably and evade normal biological processes that would typically suppress their growth.