The page on "mTOR and Nutrient Signaling" for biochemistry majors outlines learning goals to understand the role of mTOR as a regulator of cell growth and metabolism. Key areas include understanding t...The page on "mTOR and Nutrient Signaling" for biochemistry majors outlines learning goals to understand the role of mTOR as a regulator of cell growth and metabolism. Key areas include understanding the structure and function of mTOR complexes (mTORC1 and mTORC2), the upstream nutrient signals affecting mTOR activity, and the downstream cellular outcomes.
Genes that are a part of the normal regulation of cell division, but which after mutation contribute to cancer, are called proto-oncogenes. Once a proto-oncogene has been abnormally activated by mutat...Genes that are a part of the normal regulation of cell division, but which after mutation contribute to cancer, are called proto-oncogenes. Once a proto-oncogene has been abnormally activated by mutation, it is called an oncogene. More than 100 genes have been defined as proto-oncogenes. These include genes at almost every step of the signaling pathways that normally induce cell to divide, including growth factors, receptors, signal transducers, and transcription factors.
