This page delves into the fundamentals of chemical kinetics and thermodynamics within biochemistry. It explains key concepts such as reaction rates, activation energy, reaction mechanisms, the transit...This page delves into the fundamentals of chemical kinetics and thermodynamics within biochemistry. It explains key concepts such as reaction rates, activation energy, reaction mechanisms, the transition state, and how these factors, alongside thermodynamic principles like enthalpy, entropy, and Gibbs free energy, dictate reaction spontaneity and equilibrium.
This page outlines learning goals for understanding protein-ligand interactions, including binding thermodynamics, key binding constants like Kd and Ka, and the interpretation of binding curves. It co...This page outlines learning goals for understanding protein-ligand interactions, including binding thermodynamics, key binding constants like Kd and Ka, and the interpretation of binding curves. It compares one-site versus two-site binding models and explores cooperative and allosteric effects. It discusses experimental methods for measuring interactions and relates binding to protein functions in biological contexts.
