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- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/11%3A_Genomics/11.03%3A_Gene_Therapy_-_Methods_and_ProspectsThis page discusses advancements in gene therapy for treating genetic disorders, particularly single-gene diseases like SCID and β-thalassemia. It highlights successes in improving patient conditions,...This page discusses advancements in gene therapy for treating genetic disorders, particularly single-gene diseases like SCID and β-thalassemia. It highlights successes in improving patient conditions, such as reduced need for blood transfusions. The use of adenovirus vectors in gene therapy is noted for its reduced integration risks, but challenges include strong immune responses and pre-existing antibodies in patients.
- https://bio.libretexts.org/Learning_Objects/Worksheets/Book%3A_The_Biology_Corner_(Worksheets)/Cell_Biology/Case_Study%3A_Cystic_Fibrosis_-_CERHis findings, reported in a series of three recent papers in the Journal of General Physiology, detail the type and order of molecular events required to open and close the gates of the cystic fibrosi...His findings, reported in a series of three recent papers in the Journal of General Physiology, detail the type and order of molecular events required to open and close the gates of the cystic fibrosis chloride channel, or as scientists call it, the cystic fibrosis transmembrane conductance regulator (CFTR). In the case of CFTR, chloride ions travel in and out of the cell through the channel’s guarded pore as a means to control the flow of water in and out of cells.
- https://bio.libretexts.org/Courses/City_College_of_San_Francisco/Introduction_to_Microbiology_OER_-_Ying_Liu/20%3A_Microbiomes_and_One_Health/20.06%3A_The_Respiratory_MicrobiomeThis page examines the significant role of the respiratory microbiome in various pulmonary diseases, including COPD, cystic fibrosis, and asthma. It discusses how dysbiosis can worsen conditions, the ...This page examines the significant role of the respiratory microbiome in various pulmonary diseases, including COPD, cystic fibrosis, and asthma. It discusses how dysbiosis can worsen conditions, the influence of harmful bacteria during exacerbations, and the relationship between microbial diversity and respiratory infections.
- https://bio.libretexts.org/Courses/City_College_of_San_Francisco/Introduction_to_Genetics/09%3A_Mutation_and_VariationHumans have an interesting relationship with mutation. From our perspective, mutations can be extraordinarily useful, since mutations are need for evolution to occur. Mutation is essential for the dom...Humans have an interesting relationship with mutation. From our perspective, mutations can be extraordinarily useful, since mutations are need for evolution to occur. Mutation is essential for the domestication and improvement of almost all of our food. On the other hand, mutations are the cause of many cancers and other diseases, and can be devastating to individuals. The vast majority of mutations probably go undetected. In this section, we will examine some of the causes and effects of mutati
