The page on "mTOR and Nutrient Signaling" for biochemistry majors outlines learning goals to understand the role of mTOR as a regulator of cell growth and metabolism. Key areas include understanding t...The page on "mTOR and Nutrient Signaling" for biochemistry majors outlines learning goals to understand the role of mTOR as a regulator of cell growth and metabolism. Key areas include understanding the structure and function of mTOR complexes (mTORC1 and mTORC2), the upstream nutrient signals affecting mTOR activity, and the downstream cellular outcomes.
The page outlines learning goals related to protein-ligand interactions, focusing on induced fit and conformational selection, intrinsically disordered proteins (IDPs), and Molecular Recognition Featu...The page outlines learning goals related to protein-ligand interactions, focusing on induced fit and conformational selection, intrinsically disordered proteins (IDPs), and Molecular Recognition Features (MoRFs). It describes models of protein-ligand binding, explores mechanisms of coupling folding and binding, and discusses the role of intrinsic disorder in cellular functions.