This page outlines the importance of DNA repair mechanisms in living cells, detailing 130 genes involved in repair processes that counteract damage from various sources, including radiation and chemic...This page outlines the importance of DNA repair mechanisms in living cells, detailing 130 genes involved in repair processes that counteract damage from various sources, including radiation and chemicals. Key repair pathways include direct reversal, Base Excision Repair (BER), Nucleotide Excision Repair (NER), and Mismatch Repair (MMR), with specific enzymes for each.
The page outlines learning goals for understanding steroid hormones and their action mechanisms, emphasizing their lipid-soluble nature, ability to cross cell membranes, and binding to intracellular r...The page outlines learning goals for understanding steroid hormones and their action mechanisms, emphasizing their lipid-soluble nature, ability to cross cell membranes, and binding to intracellular receptors. It describes how these complexes modulate gene transcription, implying broader physiological and pathological impacts.
This page explores the fundamentals of biochemistry with a focus on protein kinases, cellular signaling, and the kinome. It covers the diversity and structural features of kinases, how they are activa...This page explores the fundamentals of biochemistry with a focus on protein kinases, cellular signaling, and the kinome. It covers the diversity and structural features of kinases, how they are activated and regulated, including the detailed mechanisms of the kinome, kinases like Protein Kinase A, Protein Kinase C, and Akt, and their roles in signal transduction related to health and disease.
