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- https://bio.libretexts.org/Workbench/Modern_Genetics/07%3A_Molecular_Genetics_I_-_Molecular_Biology_of_Gene_Expression/7.04%3A_Eukaryotic_RNA_ProcessingThe three most important steps of pre-mRNA processing are the addition of stabilizing and signaling factors at the 5′ and 3′ ends of the molecule, and the removal of intervening sequences that do not ...The three most important steps of pre-mRNA processing are the addition of stabilizing and signaling factors at the 5′ and 3′ ends of the molecule, and the removal of intervening sequences that do not specify the appropriate amino acids. This modification further protects the pre-mRNA from degradation and signals the export of the cellular factors that the transcript needs to the cytoplasm.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/01%3A_Unit_I-_Structure_and_Catalysis/06%3A_Enzyme_Activity/6.07%3A__Ribozymes_-_RNA_EnzymesThe page provides a detailed overview of ribozymes, which are RNA molecules with catalytic properties similar to protein enzymes. It covers their structure, role in catalysis, and historical significa...The page provides a detailed overview of ribozymes, which are RNA molecules with catalytic properties similar to protein enzymes. It covers their structure, role in catalysis, and historical significance, emphasizing the RNA world hypothesis where RNA preceded proteins. The section examines examples like self-splicing introns, RNase P, and the ribosome as ribozymes, explaining their mechanisms and significance in evolution and cellular regulation.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Principles_of_Biology/02%3A_Chapter_2/15%3A_Protein_Synthesis/15.04%3A_Eukaryotic_RNA_ProcessingThe three most important steps of pre-mRNA processing are the addition of stabilizing and signaling factors at the 5′ and 3′ ends of the molecule, and the removal of intervening sequences that do not ...The three most important steps of pre-mRNA processing are the addition of stabilizing and signaling factors at the 5′ and 3′ ends of the molecule, and the removal of intervening sequences that do not specify the appropriate amino acids. This modification further protects the pre-mRNA from degradation and signals the export of the cellular factors that the transcript needs to the cytoplasm.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/03%3A_Unit_III-_Information_Pathway/25%3A_RNA_Metabolism/25.02%3A_RNA_ProcessingThe page provides a comprehensive overview of RNA processing in eukaryotic cells, highlighting essential processes such as 5??? capping, RNA splicing, and polyadenylation. It explains RNA processing's...The page provides a comprehensive overview of RNA processing in eukaryotic cells, highlighting essential processes such as 5??? capping, RNA splicing, and polyadenylation. It explains RNA processing's role in transforming pre-mRNA into mature mRNA, promoting mRNA stability, nuclear export, and translation initiation. RNA splicing involves removing introns and linking exons with spliceosome assistance, while polyadenylation entails adding a poly-A tail for mRNA stability.
- https://bio.libretexts.org/Bookshelves/Genetics/Working_with_Molecular_Genetics_(Hardison)/Unit_III%3A_The_Pathway_of_Gene_Expression/12%3A_RNA_processing/12.6%3A_Splicing_of_introns_in_premRNAsAfter the 2'-OH of the A at the branch has joined to the initial G of the intron, the 3'‑OH of the upstream exon is available to react with the first nucleotide of the downstream exon, thereby joining...After the 2'-OH of the A at the branch has joined to the initial G of the intron, the 3'‑OH of the upstream exon is available to react with the first nucleotide of the downstream exon, thereby joining the two exons via the phosphoester transfer mechanism.
- https://bio.libretexts.org/Workbench/Bio_11A_-_Introduction_to_Biology_I/19%3A_Transcription/19.05%3A_Eukaryotic_RNA_ProcessingThe three most important steps of pre-mRNA processing are the addition of stabilizing and signaling factors at the 5′ and 3′ ends of the molecule, and the removal of intervening sequences that do not ...The three most important steps of pre-mRNA processing are the addition of stabilizing and signaling factors at the 5′ and 3′ ends of the molecule, and the removal of intervening sequences that do not specify the appropriate amino acids. This modification further protects the pre-mRNA from degradation and signals the export of the cellular factors that the transcript needs to the cytoplasm.