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15.2: Cranial Nerves

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    Cranial Nerves

    Cranial nerves are the nerves that emerge directly from the brain (including the brainstem), in contrast to spinal nerves (which emerge from segments of the spinal cord). Ten of the cranial nerves originate in the brainstem. Cranial nerves relay information between the brain and parts of the body, primarily to and from regions of the head and neck. Spinal nerves emerge sequentially from the spinal cord with the spinal nerve closest to the head (C1) emerging in the space above the first cervical vertebra. The cranial nerves, however, emerge from the central nervous system above this level. Each cranial nerve is paired and is present on both sides. In humans there are twelve cranial nerves pairs, which are assigned Roman numerals I–XII. The numbering of the cranial nerves is based on the order in which they emerge from the brain, front to back (brainstem).

    Diagram of connections between cranial nerves and the brain stem

    Above: Lateral view of the brain stem showing the locations of the cranial nerves III - XII.

    The, olfactory nerves (I) and optic nerves (II) emerge from the cerebrum or forebrain, and the remaining ten pairs arise from the brainstem, which is the lower part of the brain.

    Diagram of the cranial nerves

    Above: Inferior view of the brain with the pairs of cranial nerves labeled.

    The cranial nerves are considered components of the peripheral nervous system (PNS), although on a structural level the olfactory (I), optic (II), and trigeminal (V) nerves are more accurately considered part of the central nervous system (CNS).

    Humans are considered to have twelve pairs of cranial nerves (I–XII). They are: the olfactory nerve (I), the optic nerve (II), oculomotor nerve (III), trochlear nerve (IV), trigeminal nerve (V), abducens nerve (VI), facial nerve (VII), vestibulocochlear nerve (VIII), glossopharyngeal nerve (IX), vagus nerve (X), accessory nerve (XI), and hypoglossal nerve (XII).

    C.N. #

    C.N. Name

    Associated Opening(s)

    Nerve Type

    Innervation

    C.N. I

    olfactory nerve

    olfactory foramina (cribriform plate of the ethmoid bone)

    special sensory

    olfaction (smell) - olfactory epithelium

    C.N. II

    optic nerve

    optic canals

    special sensory

    retina of the eye (sight)

    C.N. III

    oculomotor nerve

    superior orbital fissure

    motor

    inferior oblique, medial rectus, superior rectus, and inferior recuts muscles of the eye

    C.N. IV

    trochlear nerve

    superior orbital fissure

    motor

    superior oblique muscle of the eye

    C.N. V

    trigeminal nerve

    C.N. V, branch 1: ophthalmic nerve

    superior orbital fissure, supraorbital foramen

    sensory

    skin on the upper third of the face

    C.N. V, branch 2: maxillary nerve

    foramen rotundum, infraorbital foramen

    sensory

    skin on the middle third of the face

    C.N. V, branch 3: mandibular nerve

    foramen ovale, mandibular foramen, mental foramen

    sensory

    skin on the lower third of the face, pain from the tongue

    C.N. VI

    abducens nerve

    superior orbital fissure

    motor

    lateral recuts muscle of the eye

    C.N. VII

    facial nerve

    internal acoustic meatus, stylomastoid foramen

    motor, special sensory

    motor: muscles of facial expression special sensory: taste buds on the anterior two-thirds of the tongue

    C.N. VIII

    vestibulocochlear nerve

    internal acoustic meatus

    special sensory

    auditory (hearing), balance, and equilibrium - inner ear (cochlear and vestibular apparatus)

    C.N. IX

    glossopharyngeal nerve

    jugular foramen

    motor, special sensory

    motor: pharynx muscles

    special sensory: taste buds on the posterior third of the tongue

    C.N. X

    vagus nerve

    jugular foramen

    motor, sensory, special sensory

    motor: heart, smooth muscle of pharynx and organs of the gut

    sensory: skin across the throat and the external acoustic meatus

    special sensory: taste, gag reflex

    C.N. XI

    accessory nerve

    jugular foramen, foramen magnum

    motor

    trapezius, sternocleidomastoid, muscles of the pharynx

    C.N. XII

    hypoglossal nerve

    hypoglossal canal

    motor

    muscles of the tongue

    Mnemonic phrases can be helpful to remember the order of the cranial nerves. Here are two popular mnemonics for the order of the cranial nerves (I-XII):

    • Oh Once One Takes The Anatomy Final, Very Good Vacations Are Heavenly
    • Oh, Oh, Oh, To Touch And Feel Very Good Velvet, A-H

    The cranial nerves carry motor, sensory, and/or special sensory signals. Motor signals innervate muscles/tissues, sensory signals send information to the CNS from sensory receptors, and special sensory signals send information to the CNS from the special senses (vision, hearing and balance, and taste). Some cranial nerves carry more than one type of signal; one cranial nerve even carries all three types of signals.

    To enter/exit the skull, cranial nerves pass through openings in the base of the skull.

    Diagram of the cranial nerves

    Above: Diagram showing how the cranial nerves enter/exit the cranial cavity through the skull.

    Cadaver image of cranial nerves

    Above: Image of cadaver with the left cranial nerves labeled.


    This page titled 15.2: Cranial Nerves is shared under a CC BY-NC-SA 4.0 license and was authored, remixed, and/or curated by Rosanna Hartline.

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