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20.8: Open Issues and Challenges

  • Page ID
    41042
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    Some of the challenges regarding the previous covered topics are

    • Validation How do we know the network structure is right?

    • How do we know if the network function is right?
    • Measuring and modeling protein expression
    • Understanding the evolution of regulatory networks

    • Mostly it is intractable to compute joint distributions so we focus on marginal distributions.

    • Often we have a very large number of regulators or targets making some of the problems require simplifying assumption to be able to make it tractable.


    This page titled 20.8: Open Issues and Challenges is shared under a CC BY-NC-SA 4.0 license and was authored, remixed, and/or curated by Manolis Kellis et al. (MIT OpenCourseWare) via source content that was edited to the style and standards of the LibreTexts platform; a detailed edit history is available upon request.