9B: Neural Signaling
- Page ID
- 4611
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Learning Objectives
- describe how a transmembrane ion gradient and nongated/gated membrane ion channels specific for given ions can give rise to a transmembrane electric potential across membranes
- given ion concentrations and the electrical potential across a membrane, predict likely changes in the membrane potential and ion concentrations on the opening of specific channnels;
- use the Goldman equation to predict transmembrane electrical potentials;
- state difference between the communication across the neuromuscular junction and a synapse between two neurons;
- state the difference between nongated and gated ion channels;
- describe different ways to open/close gated ion channels
- describe the immediate changes in the muscle cells when acetylcholine is released into the neuromuscular junction
- describe the roles of stimulatory neurotransmitter receptors, voltage-gated Na+and K+ channels and the Na/K-ATPase in the activation of a neuron;
- explain the mechanism for selectivity of K+ over the smaller Na+ ion in the K+ channel;
- briefly explain how membrane protein channels can be gated open by changes in transmembrane potential;