The advantage of writing and using an e-book is that it can be updated and corrected on a daily basis (if one is so inclined). It is impossible to keep up with all that is new in the field of biochemistry. Instead of giving up, I have developed an alternative approach. I review three journals each week: Nature, Science, and Chemical and Engineering News. If I find especially relevant and exciting new information in these journals or references found in them, I add it to the appropriate sections of Biochemistry Online.