D7. Links and References
- Page ID
- 5625
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\(\newcommand{\avec}{\mathbf a}\) \(\newcommand{\bvec}{\mathbf b}\) \(\newcommand{\cvec}{\mathbf c}\) \(\newcommand{\dvec}{\mathbf d}\) \(\newcommand{\dtil}{\widetilde{\mathbf d}}\) \(\newcommand{\evec}{\mathbf e}\) \(\newcommand{\fvec}{\mathbf f}\) \(\newcommand{\nvec}{\mathbf n}\) \(\newcommand{\pvec}{\mathbf p}\) \(\newcommand{\qvec}{\mathbf q}\) \(\newcommand{\svec}{\mathbf s}\) \(\newcommand{\tvec}{\mathbf t}\) \(\newcommand{\uvec}{\mathbf u}\) \(\newcommand{\vvec}{\mathbf v}\) \(\newcommand{\wvec}{\mathbf w}\) \(\newcommand{\xvec}{\mathbf x}\) \(\newcommand{\yvec}{\mathbf y}\) \(\newcommand{\zvec}{\mathbf z}\) \(\newcommand{\rvec}{\mathbf r}\) \(\newcommand{\mvec}{\mathbf m}\) \(\newcommand{\zerovec}{\mathbf 0}\) \(\newcommand{\onevec}{\mathbf 1}\) \(\newcommand{\real}{\mathbb R}\) \(\newcommand{\twovec}[2]{\left[\begin{array}{r}#1 \\ #2 \end{array}\right]}\) \(\newcommand{\ctwovec}[2]{\left[\begin{array}{c}#1 \\ #2 \end{array}\right]}\) \(\newcommand{\threevec}[3]{\left[\begin{array}{r}#1 \\ #2 \\ #3 \end{array}\right]}\) \(\newcommand{\cthreevec}[3]{\left[\begin{array}{c}#1 \\ #2 \\ #3 \end{array}\right]}\) \(\newcommand{\fourvec}[4]{\left[\begin{array}{r}#1 \\ #2 \\ #3 \\ #4 \end{array}\right]}\) \(\newcommand{\cfourvec}[4]{\left[\begin{array}{c}#1 \\ #2 \\ #3 \\ #4 \end{array}\right]}\) \(\newcommand{\fivevec}[5]{\left[\begin{array}{r}#1 \\ #2 \\ #3 \\ #4 \\ #5 \\ \end{array}\right]}\) \(\newcommand{\cfivevec}[5]{\left[\begin{array}{c}#1 \\ #2 \\ #3 \\ #4 \\ #5 \\ \end{array}\right]}\) \(\newcommand{\mattwo}[4]{\left[\begin{array}{rr}#1 \amp #2 \\ #3 \amp #4 \\ \end{array}\right]}\) \(\newcommand{\laspan}[1]{\text{Span}\{#1\}}\) \(\newcommand{\bcal}{\cal B}\) \(\newcommand{\ccal}{\cal C}\) \(\newcommand{\scal}{\cal S}\) \(\newcommand{\wcal}{\cal W}\) \(\newcommand{\ecal}{\cal E}\) \(\newcommand{\coords}[2]{\left\{#1\right\}_{#2}}\) \(\newcommand{\gray}[1]{\color{gray}{#1}}\) \(\newcommand{\lgray}[1]{\color{lightgray}{#1}}\) \(\newcommand{\rank}{\operatorname{rank}}\) \(\newcommand{\row}{\text{Row}}\) \(\newcommand{\col}{\text{Col}}\) \(\renewcommand{\row}{\text{Row}}\) \(\newcommand{\nul}{\text{Nul}}\) \(\newcommand{\var}{\text{Var}}\) \(\newcommand{\corr}{\text{corr}}\) \(\newcommand{\len}[1]{\left|#1\right|}\) \(\newcommand{\bbar}{\overline{\bvec}}\) \(\newcommand{\bhat}{\widehat{\bvec}}\) \(\newcommand{\bperp}{\bvec^\perp}\) \(\newcommand{\xhat}{\widehat{\xvec}}\) \(\newcommand{\vhat}{\widehat{\vvec}}\) \(\newcommand{\uhat}{\widehat{\uvec}}\) \(\newcommand{\what}{\widehat{\wvec}}\) \(\newcommand{\Sighat}{\widehat{\Sigma}}\) \(\newcommand{\lt}{<}\) \(\newcommand{\gt}{>}\) \(\newcommand{\amp}{&}\) \(\definecolor{fillinmathshade}{gray}{0.9}\)Huang, J and Manning, B. The TSC1–TSC2 complex: a molecular switchboard controlling cell growth Biochem J. 2008 Jun 1; 412(2): 179–190. doi: 10.1042/BJ20080281
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Buel, G and Blenis, J. mTORC1 specificity. Science 01 Jan 2016: Vol. 351, Issue 6268, pp. 25-26 DOI: 10.1126/science.aad9696
Aylett. C. et al 1. Architecture of human mTOR complex 1Science 01 Jan 2016: Vol. 351, Issue 6268, pp. 48-52 DOI: 10.1126/science.aaa3870
Haijuan Yang, Derek G. Rudge, Joseph D. Koos, Bhamini Vaidialingam, Hyo J. Yang & Nikola P. Pavletich. mTOR kinase structure, mechanism and regulation Nature 497, 217–223 (09 May 2013) doi:10.1038/nature12122
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Quinn, W and Birnbaum, M. Distinct mTORC1 pathways for transcription and cleavage of SREBP-1c PNAS | October 2, 2012 | vol. 109 | no. 40 www.pnas.org/cgi/doi/10.1073/pnas.1214113109
Buel G. and Blenis, J. Seeing mTORC1 specificity: Structural information reveals how a multiprotein complex responds to amino acid abundance
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Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway By Robert A. Saxton, Kevin E. Knockenhauer, Rachel L. Wolfson, Lynne Chantranupong, Michael E. Pacold, Tim Wang, Thomas U. Schwartz, David M. Sabatini Science01 Jan 2016 : 53-58
Wolfson, R. et al Sestrin2 is a leucine sensor for the mTORC1 pathway Science01 Jan 2016 : 43-48
Buel, G and Blenis, J. Seeing mTORC1 specificity. Science01 Jan 2016 : 25-26
Dibble, C and Manning. B. Signal integration by mTORC1 coordinates nutrient input with biosynthetic output. NATURE CELL BIOLOGY VOLUME 15 | NUMBER 6 | JUNE 2013 pg 555
Katiyar, S. et al. REDD1, an inhibitor of mTOR signalling, is regulated by the CUL4A–DDB1 ubiquitin ligase. EMBO Rep. 2009 Aug; 10(8): 866–872. doi: 10.1038/embor.2009.93
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