9C: Signaling Proteins
- Page ID
- 4612
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Learning Objectives
- define kinases and phosphatases and their role in signal transduction
- define primary and secondary messengers and give specific examples of each
- describe the role of G proteins in coupling ligand induced conformational changes in the bound receptor to activation of specific effector proteins such as adenylate cyclase and phospholipase
- differentiate between kinases activated by second messengers and those activated by primary messengers (ligand-gated receptor Tyr kinases)
- describe the structural characteristics of G protein coupled serpentine receptors and ligand gated receptor tyrosine kinases
- draw a diagram showing the general features of kinases mediated signal transduction pathways that lead to activation of gene expression
- differentiate between neuron responses mediated by neurotransmitters on binding gated receptor/ion channels compares to G-protein coupled receptors
Estonian Translation √ by Anna Galovich