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- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/Unit_IV_-_Special_Topics/28%3A_Biosignaling_-_Capstone_Volume_I/28.14%3A_Programmed_Cell_DeathThe page provides an in-depth exploration of programmed cell death, focusing particularly on apoptosis, its mechanisms, and its significance in health and disease. It distinguishes apoptosis from othe...The page provides an in-depth exploration of programmed cell death, focusing particularly on apoptosis, its mechanisms, and its significance in health and disease. It distinguishes apoptosis from other cell death types such as autophagy and necroptosis, outlining apoptosis's intrinsic and extrinsic pathways, including involved proteins like caspases and Bcl-2 family.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/05%3A_DNA/5.13%3A_DNA_RepairThis page outlines the importance of DNA repair mechanisms in living cells, detailing 130 genes involved in repair processes that counteract damage from various sources, including radiation and chemic...This page outlines the importance of DNA repair mechanisms in living cells, detailing 130 genes involved in repair processes that counteract damage from various sources, including radiation and chemicals. Key repair pathways include direct reversal, Base Excision Repair (BER), Nucleotide Excision Repair (NER), and Mismatch Repair (MMR), with specific enzymes for each.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/12%3A_Cancer/12.01%3A_Cancer_in_GeneralThis page discusses cancer as a disease of uncontrolled cell proliferation, distinct from benign growths due to its ability to metastasize. Originating from mutated cells, cancers involve genetic dive...This page discusses cancer as a disease of uncontrolled cell proliferation, distinct from benign growths due to its ability to metastasize. Originating from mutated cells, cancers involve genetic diversity and are driven by cancer stem cells. Common causes include DNA-damaging agents and viruses, although cancer itself is not contagious. Notably, certain viral infections can elevate cancer risk.
- https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/General_Biology_(Boundless)/10%3A_Cell_Reproduction/10.04%3A_Cancer_and_the_Cell_Cycle/10.4B%3A_Tumor_Suppressor_GenesTumor-suppressor genes keep regulatory mechanisms of cell division under control and prevent abnormal cell growth.
