This page explains the determination of blood groups through surface molecules on red blood cells, focusing on the ABO and Rh systems. It highlights the significance of ABO groups (A, B, AB, O) in saf...This page explains the determination of blood groups through surface molecules on red blood cells, focusing on the ABO and Rh systems. It highlights the significance of ABO groups (A, B, AB, O) in safe blood transfusions and the importance of Rh antigens, particularly the D antigen, to prevent incompatibility issues such as erythroblastosis fetalis. The page also mentions other blood group antigens that can trigger reactions during transfusions.