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- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/01%3A_Unit_I-_Structure_and_Catalysis/06%3A_Enzyme_Activity/6.05A%3A_Enzyme_Reaction_Mechanisms_-_Arrow_PushingThis page outlines learning goals for biochemistry students on enzyme catalysis, covering mechanisms and roles of enzymes, particularly focusing on serine proteases like chymotrypsin and their catalyt...This page outlines learning goals for biochemistry students on enzyme catalysis, covering mechanisms and roles of enzymes, particularly focusing on serine proteases like chymotrypsin and their catalytic strategies. It details the function of magnesium in phosphate transfer, the classification of proteases, and the mechanisms of specific enzymes like carboxypeptidase A and lysozyme.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/Unit_IV_-_Special_Topics/28%3A_Biosignaling_-_Capstone_Volume_I/28.03%3A_The_Next_step_-_The_Kinome_and_Activation_of_Kinases_at_the_Cell_MembraneThis page explores the fundamentals of biochemistry with a focus on protein kinases, cellular signaling, and the kinome. It covers the diversity and structural features of kinases, how they are activa...This page explores the fundamentals of biochemistry with a focus on protein kinases, cellular signaling, and the kinome. It covers the diversity and structural features of kinases, how they are activated and regulated, including the detailed mechanisms of the kinome, kinases like Protein Kinase A, Protein Kinase C, and Akt, and their roles in signal transduction related to health and disease.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/02%3A_Unit_II-_Bioenergetics_and_Metabolism/21%3A_Lipid_Biosynthesis/21.02%3A_Biosynthesis_of_TriacylglycerolsThe content provides an in-depth exploration of triacylglycerol biosynthesis, its regulatory mechanisms, and role in energy storage and metabolism across various organisms. It details the enzymatic st...The content provides an in-depth exploration of triacylglycerol biosynthesis, its regulatory mechanisms, and role in energy storage and metabolism across various organisms. It details the enzymatic steps involved in the pathways, such as GPAT, AGPAT, and DGAT, and highlights the significance of lipid droplets in storing energy and sequestering potentially harmful lipids.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/01%3A_Unit_I-_Structure_and_Catalysis/06%3A_Enzyme_Activity/6.01%3A_How_Enzymes_WorkThe page outlines the fundamental principles of enzyme catalysis, describing how enzymes lower activation energies and stabilize transition states. It emphasizes various catalytic mechanisms such as a...The page outlines the fundamental principles of enzyme catalysis, describing how enzymes lower activation energies and stabilize transition states. It emphasizes various catalytic mechanisms such as acid-base, covalent, and metal ion catalysis. The page also examines the role of enzyme structure in function, the importance of binding energy, and the interplay between thermodynamics and kinetics in enzyme reactions.
- https://bio.libretexts.org/Bookshelves/Biochemistry/Fundamentals_of_Biochemistry_(Jakubowski_and_Flatt)/01%3A_Unit_I-_Structure_and_Catalysis/06%3A_Enzyme_Activity/6.05B%3A_Quantitative_Analysis_of_Enzyme_Reaction_Mechanisms_-_Serine_ProteasesThis page explores enzyme mechanisms, focusing on serine proteases like chymotrypsin, and how structural, kinetic, and thermodynamic factors influence catalysis. It covers the reaction dynamics, enzym...This page explores enzyme mechanisms, focusing on serine proteases like chymotrypsin, and how structural, kinetic, and thermodynamic factors influence catalysis. It covers the reaction dynamics, enzyme efficiency improvements, and the effects of inhibitors and solvents on enzyme activity. Insights include the importance of conformational flexibility, the effect of nonpolar solvents for catalysis, and thermodynamic factors affecting the stability of bound and transition state analog ligands.
