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  • https://bio.libretexts.org/Courses/Portland_Community_College/Cascade_Microbiology/02%3A_How_We_See_the_Invisible_World/2.2%3A_Peering_into_the_Invisible_World
    Italian scholar Girolamo Fracastoro is regarded as the first person to formally postulate that disease was spread by tiny invisible seminaria. He proposed that these seeds could attach themselves to c...Italian scholar Girolamo Fracastoro is regarded as the first person to formally postulate that disease was spread by tiny invisible seminaria. He proposed that these seeds could attach themselves to certain objects  that supported their transfer from person to person. However, since the technology for seeing such tiny objects did not yet exist, the existence of the seminaria remained hypothetical for a little over a century—an invisible world waiting to be revealed.

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