Human skin consists of two main layers, the epidermis and dermis, which are situated on top of the hypodermis, a layer of connective tissue. The skin is an effective physical barrier against microbial...Human skin consists of two main layers, the epidermis and dermis, which are situated on top of the hypodermis, a layer of connective tissue. The skin is an effective physical barrier against microbial invasion. The skin’s relatively dry environment and normal microbiota discourage colonization by transient microbes. The skin’s normal microbiota varies from one region of the body to another. The conjunctiva of the eye is a frequent site for microbial infection and deeper infections are less commo