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  • https://bio.libretexts.org/Courses/City_College_of_San_Francisco/Introduction_to_Genetics/04%3A_Mendelian_Genetics/4.08%3A_Pedigree_Analysis/4.8.03%3A_Sporadic_and_Non-Heritable_Diseases
    On the other hand, some non-genetic diseases may appear to be heritable because they affect multiple members of the same family, but this is due to the family members being exposed to the same toxins ...On the other hand, some non-genetic diseases may appear to be heritable because they affect multiple members of the same family, but this is due to the family members being exposed to the same toxins or other environmental factors (e.g., in their homes). One example of this is Amyotrophic lateral sclerosis (ALS); approximately 5–10% of cases are inherited in an AD pattern, while most of the remaining cases appear to be sporadic, in other words, not caused by a mutation inherited from a parent.

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